Literature DB >> 5762278

Papillary necrosis in experimental analgesic nephropathy.

B M Saker, P Kincaid-Smith.   

Abstract

A proprietary aspirin, phenacetin, and caffeine preparation given to rats in a dose equivalent to that taken by patients with analgesic nephropathy produced papillary necrosis in 55%. There was a higher incidence in rats deprived of fluids overnight.Papillary necrosis was not noted in rats receiving twice as much phenacetin.These findings support the argument that phenacetin should not be singled out as the substance responsible for analgesic nephropathy in man.

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 5762278      PMCID： PMC1982286          DOI： 10.1136/bmj.1.5637.161

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  11 in total

1.  ACUTE RENAL FAILURE CAUSED BY AMINOPYRINE.

Authors:  G EKNOYAN; J L MATSON
Journal:  JAMA       Date:  1964-12-07       Impact factor: 56.272

2.  RENAL PAPILLARY NECROSIS. A CLINICAL SURVEY OF SIXTY-SIX CASES.

Authors:  B HARVALD
Journal:  Am J Med       Date:  1963-10       Impact factor: 4.965

3.  EFFECTS OF ACETYLSALICYLIC ACID, PHENACETIN, PARACETAMOL, AND CAFFEINE ON RENAL TUBULAR EPITHELIUM.

Authors:  L F PRESCOTT
Journal:  Lancet       Date:  1965-07-17       Impact factor: 79.321

4.  [Papillitis necroticans renalis & hemolytic anemia in a phenazone addict].

Authors:  U AXELSSON
Journal:  Nord Med       Date:  1958-06-26

5.  Pathogenesis of the renal lesion associated with the abuse of analgesics.

Authors:  P Kincaid-Smith
Journal:  Lancet       Date:  1967-04-22       Impact factor: 79.321

6.  Short-term study of the effect of phenacetin, phenazone and amidopyrine on the rat kidney.

Authors:  D M Brown; T L Hardy
Journal:  Br J Pharmacol Chemother       Date:  1968-01

7.  Renal abnormalities in rheumatoid arthritis.

Authors:  R J Bulger; L A Healey; P Polinsky
Journal:  Ann Rheum Dis       Date:  1968-07       Impact factor: 19.103

8.  Renal disease and drug therapy in rheumatoid arthritis.

Authors:  A A Lawson; N Maclean
Journal:  Ann Rheum Dis       Date:  1966-09       Impact factor: 19.103

9.  Migraine, gastritis and renal papillary necrosis. A syndrome in chronic nonobstructive pyelonephritis.

Authors:  O Olafsson; K R Gudmundsson; A Brekkan
Journal:  Acta Med Scand       Date:  1966-01

10.  Analgesic nephropathy in perspective.

Authors:  P Kincaid-Smith
Journal:  Med J Aust       Date:  1967-08-12       Impact factor: 7.738
View more
  20 in total

1.  Renal tubular transport of paracetamol and its conjugates in the dog.

Authors:  G G Duggin; G H Mudge
Journal:  Br J Pharmacol       Date:  1975-07       Impact factor: 8.739

2.  Editorial: Choice of a mild analgesic.

Authors: 
Journal:  Br Med J       Date:  1974-06-01

3.  Drug-induced nephropathies.

Authors:  H C Burry
Journal:  Proc R Soc Med       Date:  1973-09

4.  Urinary tract infection in patients with rheumatoid arthritis.

Authors:  A G Mowat; T E Hothersall; J C Gould
Journal:  Ann Rheum Dis       Date:  1970-03       Impact factor: 19.103

Review 5.  Rheumatoid arthritis: extra-articular manifestations.

Authors:  F D Hart
Journal:  Br Med J       Date:  1969-07-19

6.  Dose-dependent change in the pattern of phenacetin metabolism in man and its possible significance in analgesic nephropathy.

Authors:  J Raaflaub; U C Dubach
Journal:  Klin Wochenschr       Date:  1969-12-01

7.  Renal medullary necrosis.

Authors: 
Journal:  Br Med J       Date:  1970-07-18

8.  Analgesic nephropathy.

Authors: 
Journal:  Br Med J       Date:  1970-10-17

9.  N-phenyl anthranilic acid: an agent for inducing and studying renal papillary necrosis in the rat.

Authors:  T L Hardy
Journal:  Br J Exp Pathol       Date:  1970-08

10.  Aspirin and analgesic nephropathy.

Authors:  A F Macklon; A W Craft; M Thompson; D N Kerr
Journal:  Br Med J       Date:  1974-03-30
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.