Literature DB >> 533765

Local anesthetics block induction of the Pseudomonas alk regulon.

S A Benson.   

Abstract

The local anesthetics procaine and piperocaine blocked induction of the plasmid-determined enzymatic activities involved in the metabolism of n-alkanes in Pseudomonas putida. Procaine reversibly inhibited existing alkane hydroxylase activity. Induction of a soluble aliphatic amidase activity was not affected. These results support the hypothesis that induction of the plasmid-determined alkane metabolic system in P. putida involves a membrane component(s).

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Year:  1979        PMID： 533765      PMCID： PMC216764          DOI： 10.1128/jb.140.3.1123-1125.1979

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  10 in total

1.  Induction of alkane hydroxylase proteins by unoxidized alkane in Pseudomonas putida.

Authors:  S Benson; J Shapiro
Journal:  J Bacteriol       Date:  1975-08       Impact factor: 3.490

Review 2.  The membrane actions of anesthetics and tranquilizers.

Authors:  P Seeman
Journal:  Pharmacol Rev       Date:  1972-12       Impact factor: 25.468

Review 3.  Studies on the mechanism of action of local anesthetics with phospholipid model membranes.

Authors:  D Papahadjopoulos
Journal:  Biochim Biophys Acta       Date:  1972-04-18

4.  Biochemical and genetic studies with regulator mutants of the Pseudomonas aeruginosa 8602 amidase system.

Authors:  W J Brammar; P H Clarke; A J Skinner
Journal:  J Gen Microbiol       Date:  1967-04

5.  Plasmid-determined alcohol dehydrogenase activity in alkane-utilizing strains of Pseudomonas putida.

Authors:  S Benson; J Shapiro
Journal:  J Bacteriol       Date:  1976-05       Impact factor: 3.490

6.  Depression of phase-transition temperature in a model cell membrane by local anesthetics.

Authors:  I Ueda; C Tashiro; K Arakawa
Journal:  Anesthesiology       Date:  1977-05       Impact factor: 7.892

7.  Regulation of alkane oxidation in Pseudomonas putida.

Authors:  A Grund; J Shapiro; M Fennewald; P Bacha; J Leahy; K Markbreiter; M Nieder; M Toepfer
Journal:  J Bacteriol       Date:  1975-08       Impact factor: 3.490

8.  Induction of alkaline phosphatase in Escherichia coli: effect of procaine hydrochloride.

Authors:  R C Tribhuwan; D S Pradhan
Journal:  J Bacteriol       Date:  1977-08       Impact factor: 3.490

9.  Regulatory mutations of the Pseudomonas plasmid alk regulon.

Authors:  M Fennewald; J Shapiro
Journal:  J Bacteriol       Date:  1977-11       Impact factor: 3.490

10.  Fractionation of inducible alkane hydroxylase activity in Pseudomonas putida and characterization of hydroxylase-negative plasmid mutations.

Authors:  S Benson; M Fennewald; J Shapiro; C Huettner
Journal:  J Bacteriol       Date:  1977-11       Impact factor: 3.490
  10 in total
  3 in total

1.  Toluene induction and uptake kinetics and their inclusion in the specific-affinity relationship for describing rates of hydrocarbon metabolism.

Authors:  B R Robertson; D K Button
Journal:  Appl Environ Microbiol       Date:  1987-09       Impact factor: 4.792

2.  Local anesthetics block transient expression of inducible functions for transformation in Streptococcus sanguis.

Authors:  J L Raina
Journal:  J Bacteriol       Date:  1983-10       Impact factor: 3.490

3.  Selective inhibition of carbohydrate transport by the local anesthetic procaine in Escherichia coli.

Authors:  S Granett; M Villarejo
Journal:  J Bacteriol       Date:  1981-08       Impact factor: 3.490
  3 in total

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