Literature DB >> 328482

Induction of alkaline phosphatase in Escherichia coli: effect of procaine hydrochloride.

R C Tribhuwan, D S Pradhan.   

Abstract

The effect of procaine hydrochloride, an anesthetic known to alter membrane structure, on the induced formation of alkaline phosphatase, a periplasmic enzyme, in Escherichia coli was investigated. Procaine hydrochloride specifically arrested the appearance of active alkaline phosphatase while permitting the induction of another enzyme, beta-galactosidase, which is internally localized. Evidence has been obtained to show that procaine hydrochloride does not arrest synthesis of inactive monomer subunits of the enzyme, indicating that the drug interferes in the conversion of monomer subunits to an active dimer enzyme.

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Year:  1977        PMID: 328482      PMCID: PMC235448          DOI: 10.1128/jb.131.2.431-437.1977

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  15 in total

1.  Effect of procaine hydrochloride on DNA repair in Escherichia coli.

Authors:  C K Nair; D S Pradhan
Journal:  Chem Biol Interact       Date:  1975-09       Impact factor: 5.192

2.  DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.

Authors:  B J DAVIS
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

3.  Influence of inorganic phosphate in the formation of phosphatases by Escherichia coli.

Authors:  A TORRIANI
Journal:  Biochim Biophys Acta       Date:  1960-03-11

4.  Isolation and properties of bacteria capable of high rates of beta-galactosidase synthesis.

Authors:  T HORIUCHI; J I TOMIZAWA; A NOVICK
Journal:  Biochim Biophys Acta       Date:  1962-01-22

5.  Reactivation and hybridization of reduced alkaline phosphatase.

Authors:  C LEVINTHAL; E R SIGNER; K FETHEROLF
Journal:  Proc Natl Acad Sci U S A       Date:  1962-07-15       Impact factor: 11.205

6.  Mutants of Escherichia coli requiring methionine or vitamin B12.

Authors:  B D DAVIS; E S MINGIOLI
Journal:  J Bacteriol       Date:  1950-07       Impact factor: 3.490

Review 7.  Studies on the mechanism of action of local anesthetics with phospholipid model membranes.

Authors:  D Papahadjopoulos
Journal:  Biochim Biophys Acta       Date:  1972-04-18

8.  In vitro synthesis of Escherichia coli alkaline phosphatase monomers.

Authors:  F C Dohan; R H Rubman; A Torriani
Journal:  J Mol Biol       Date:  1971-06-14       Impact factor: 5.469

9.  Alkaline phosphatase subunits and their dimerization in vivo.

Authors:  A Torriani
Journal:  J Bacteriol       Date:  1968-10       Impact factor: 3.490

10.  Mechanism of action of phenethyl alcohol: breakdown of the cellular permeability barrier.

Authors:  S Silver; L Wendt
Journal:  J Bacteriol       Date:  1967-02       Impact factor: 3.490

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  13 in total

1.  Effect of environmental toxicants on enzyme biosynthesis: a comparison of beta-galactosidase, alpha-glucosidase and tryptophanase.

Authors:  R J Dutton; G Bitton; B Koopman; O Agami
Journal:  Arch Environ Contam Toxicol       Date:  1990 May-Jun       Impact factor: 2.804

2.  Preferential suppression of normal exoenzyme formation by membrane-modifying agents.

Authors:  Y Fishman; S Rottem; N Citri
Journal:  J Bacteriol       Date:  1980-03       Impact factor: 3.490

3.  envZ mediates transcriptional control by local anesthetics but is not required for osmoregulation in Escherichia coli.

Authors:  M Villarejo; C C Case
Journal:  J Bacteriol       Date:  1984-09       Impact factor: 3.490

4.  Sequence of the regulatory region of omp T, the gene specifying major outer membrane protein a (3b) of Escherichia coli K-12: implications for regulation and processing.

Authors:  G Gordon; R C Gayda; A Markovitz
Journal:  Mol Gen Genet       Date:  1984

5.  Isolation and characterization of chain-terminating nonsense mutations in a porin regulator gene, envZ.

Authors:  S Garrett; R K Taylor; T J Silhavy
Journal:  J Bacteriol       Date:  1983-10       Impact factor: 3.490

6.  Effects of local anesthetics on bacterial cells.

Authors:  M T Silva; J C Sousa; J J Polónia; P M Macedo
Journal:  J Bacteriol       Date:  1979-01       Impact factor: 3.490

7.  Bacterial alkaline phosphatase clonal variation in some Escherichia coli K-12 phoR mutant strains.

Authors:  B L Wanner
Journal:  J Bacteriol       Date:  1986-12       Impact factor: 3.490

8.  Local anesthetics block induction of the Pseudomonas alk regulon.

Authors:  S A Benson
Journal:  J Bacteriol       Date:  1979-12       Impact factor: 3.490

9.  Neuroactive drugs inhibit trypsin and outer membrane protein processing in Escherichia coli K-12.

Authors:  R C Gayda; G W Henderson; A Markovitz
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

10.  Cotranslational secretion of diphtheria toxin and alkaline phosphatase in vitro: involvement of membrane protein(s).

Authors:  W P Smith
Journal:  J Bacteriol       Date:  1980-03       Impact factor: 3.490

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