Literature DB >> 5288771

Structure of the poly(G) polymerase component of the bacteriophage f2 replicase.

N V Fedoroff, N D Zinder.   

Abstract

A rifampicin-resistant poly(G) polymerase has been purified from f2 sus 11-infected cells. The poly(G) polymerase is believed to represent part of the f2 replicase on the basis of several criteria. It is present only in infected cells and shares the characteristic rifampicin resistance of crude f2 replicase activity. Partially purified poly(G) polymerase preparations exhibit replicase activity, synthesizing f2 "lus"strand RNA from denatured, partially double-stranded f2 RNA template. Highly purified poly(G) polymerase preparations, although lacking replicase activity, contain a protein which is electrophoretically identical to the protein product of the viral replicase cistron.

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Year:  1971        PMID: 5288771      PMCID: PMC389304          DOI: 10.1073/pnas.68.8.1838

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  24 in total

1.  HOST-DEPENDENT MUTANTS OF THE BACTERIOPHAGE F2. IV. ON THE BIOSYNTHESIS OF A VIRAL RNA POLYMERASE.

Authors:  H F LODISH; S COOPER; N D ZINDER
Journal:  Virology       Date:  1964-09       Impact factor: 3.616

2.  Purification and properties of nascent f2 phage ribonucleic acid.

Authors:  H D Robertson; N D Zinder
Journal:  J Biol Chem       Date:  1969-11-10       Impact factor: 5.157

3.  Replication of RNA viruses. X. Replication of a natural 6 s RNA by the Q-beta RNA polymerase.

Authors:  A K Banerjee; U Rensing; J T August
Journal:  J Mol Biol       Date:  1969-10-28       Impact factor: 5.469

4.  A new method for the large scale purification of Escherichia coli deoxyribonucleic acid-dependent ribonucleic acid polymerase.

Authors:  R R Burgess
Journal:  J Biol Chem       Date:  1969-11-25       Impact factor: 5.157

5.  Synthesis of virus-specific proteins in Escherichia coli infected with the RNA bacteriophage MS2.

Authors:  E Viñuela; I D Algranati; S Ochoa
Journal:  Eur J Biochem       Date:  1967-03

6.  Asynchronous synthesis of the complementary strands of the reovirus genome.

Authors:  M Schonberg; S C Silverstein; D H Levin; G Acs
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205

7.  The dissociation of Q-beta-replicase and the relation of one of the components to a poly-C-dependent poly-G-polymerase.

Authors:  T S Eikhom; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1967-06       Impact factor: 11.205

8.  Amber mutants and chain termination in vitro.

Authors:  R E Webster; D L Engelhardt; N D Zinder; W Konigsberg
Journal:  J Mol Biol       Date:  1967-10-14       Impact factor: 5.469

9.  Mutants of the bacteriophage f2. 8. Control mechanisms for phage-specific syntheses.

Authors:  H F Lodish; N D Zinder
Journal:  J Mol Biol       Date:  1966-08       Impact factor: 5.469

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  14 in total

1.  Discriminative effect of rifampin of RNA replication of various RNA bacteriophages.

Authors:  H Engelberg; I Brudo; M Israeli-Reches
Journal:  J Virol       Date:  1975-08       Impact factor: 5.103

2.  The synthetase gene of the RNA phages R17, MS2 and f2 has a single UAG terminator codon.

Authors:  J F Atkins; R F Gesteland
Journal:  Mol Gen Genet       Date:  1975-08-05

3.  R17 bacteriophage replicase: association with the inhibition of Qbeta, fd bacteriophage and beta-galactosidase production.

Authors:  J W Scott; W J Iglewski
Journal:  J Virol       Date:  1975-10       Impact factor: 5.103

4.  Affinity adsorbents consisting of nucleic acids immobilized via bisoxirane activated polysaccharides.

Authors:  H Potuzak; P D Dean
Journal:  Nucleic Acids Res       Date:  1978-01       Impact factor: 16.971

5.  Isolation and properties of the replicase of encephalomyocarditis virus.

Authors:  A Traub; B Duskin; H Rosenberg; E Kalmar
Journal:  J Virol       Date:  1976-05       Impact factor: 5.103

6.  Specific binding of messenger RNA and methionyl-tRNAfMet by the same initiation factor for eukaryotic protein synthesis.

Authors:  R Kaempfer; R Hollender; W R Abrams; R Israeli
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

7.  Template specificity of Qbeta and SP phage RNA replicases as studied by replication of small variant RNAs.

Authors:  Y Fukami; I Haruna
Journal:  Mol Gen Genet       Date:  1979-01-31

8.  Requirement of chain initiation factor 3 and ribosomal protein S1 in translation of synthetic and natural messenger RNA.

Authors:  J E Sobura; M R Chowdhury; D A Hawley; A J Wahba
Journal:  Nucleic Acids Res       Date:  1977-01       Impact factor: 16.971

9.  Deductive analysis of a protein-synthesis mutant of Escherichia coli.

Authors:  D Patterson; D Gillespie
Journal:  Biochem Genet       Date:  1973-02       Impact factor: 1.890

10.  An Escherichia coli mutant with a temperature-sensitive function affecting bacteriophage Qbeta RNA replication.

Authors:  N C Mandal; P M Silverman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

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