Literature DB >> 526006

LY127935, a new beta-lactam antibiotic, versus Proteus, Klebsiella, Serratia, and Pseudomonas.

D J Flournoy, F A Perryman.   

Abstract

One hundred eight clinical isolates of Proteus, Klebsiella, Serratia, and Pseudomonas spp. were tested in vitro against LY127935, cefamandole, cefoxitin, ticarcillin, carbenicillin, gentamicin, tobramycin, and amikacin by broth microdilution. The activities of LY127935 were greater than or equal to those of the other antimicrobial agents against Proteus vulgaris, Klebsiella pneumoniae, and Serratia marcescens. Inhibitions were greatest, however, for ticarcillin and carbenicillin versus Proteus morganii and gentamicin versus Pseudomonas aeruginosa.

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Year:  1979        PMID： 526006      PMCID： PMC352921          DOI： 10.1128/AAC.16.5.641

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Variation in response of Pseudomonas aeruginosa to combinations of gentamicin and carbenicillin.

Authors:  D J Flournoy; K M Cunningham; E R Rhoades
Journal:  J Okla State Med Assoc       Date:  1979-05

2.  Comparison of in vitro antimicrobial activity of cefamandole and cefazolin with cephalothin against over 8,000 clinical bacterial isolates.

Authors:  R N Jones; P C Fuchs
Journal:  Antimicrob Agents Chemother       Date:  1976-06       Impact factor: 5.191

3.  Antibiotic susceptibility testing by a standardized single disk method.

Authors:  A W Bauer; W M Kirby; J C Sherris; M Turck
Journal:  Am J Clin Pathol       Date:  1966-04       Impact factor: 2.493

4.  Comparative in vitro activity of newer cephalosporins against anaerobic bacteria.

Authors:  A W Chow; D Bednorz
Journal:  Antimicrob Agents Chemother       Date:  1978-11       Impact factor: 5.191

5.  In vitro evaluation of cefoxitin and cefamandole.

Authors:  H G Adams; G A Stilwell; M Turck
Journal:  Antimicrob Agents Chemother       Date:  1976-06       Impact factor: 5.191

6.  Comparison between agar and broth minimum inhibitory concentrations of cefamandole, Cefoxitin, and cefuroxime.

Authors:  M Rylander; J E Brorson; J Johnsson; R Norrby
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191
  6 in total
  9 in total

1.  Single- and multiple-dose pharmacokinetics of moxalactam in normal subjects.

Authors:  K S Israel; H R Black; G L Brier; J D Wolny; K A DeSante
Journal:  Antimicrob Agents Chemother       Date:  1982-07       Impact factor: 5.191

2.  Comparison of antimicrobial susceptibility patterns among coagulase-negative staphylococci.

Authors:  S B Price; D J Flournoy
Journal:  Antimicrob Agents Chemother       Date:  1982-03       Impact factor: 5.191

3.  Profile of patients from a Veterans Administration medical center.

Authors:  D J Flournoy; L Adkins
Journal:  J Natl Med Assoc       Date:  1988-05       Impact factor: 1.798

4.  Superior activity of N-formimidoyl thienamycin against gentamicin-resistant Pseudomonas aeruginosa.

Authors:  P R Michael; R H Alford; Z A McGee
Journal:  Antimicrob Agents Chemother       Date:  1981-11       Impact factor: 5.191

5.  Tentative interpretive standards for disk susceptibility tests with moxalactam (LY127935).

Authors:  A L Barry; C Thornsberry; R N Jones; E H Gerlach
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

6.  Comparative susceptibilities of clinical isolates of Serratia marcescens to newer cephalosporins, alone and in combination with various aminoglycosides.

Authors:  S M Markowitz; D J Sibilla
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

7.  Randomized comparative study of moxalactam and cefazolin in the treatment of acute urinary tract infections in adults.

Authors:  A S Lea; A W Sudan; B A Wood; L O Gentry
Journal:  Antimicrob Agents Chemother       Date:  1982-07       Impact factor: 5.191

8.  Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

Authors:  W K Bolton; W M Scheld; D A Spyker; T L Overby; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1980-12       Impact factor: 5.191

9.  Pharmacokinetics of moxalactam in subjects with normal and impaired renal function.

Authors:  A Leroy; G Humbert; J P Fillastre
Journal:  Antimicrob Agents Chemother       Date:  1981-06       Impact factor: 5.191
  9 in total

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