Literature DB >> 520822

The Ah locus: biochemical basis for genetic differences in brain tumor formation in mice.

R C Levitt, J M Fysh, N M Jensen, D W Nebert.   

Abstract

Allelic differences at the Ah locus are showen to exist in the mouse brain. This finding probably explains inbred mouse strain differences in polycyclic hydrocarbon tumorigenesis of the brain described more than 35 years ago and may be important in understanding the etiology of genetic differences in certain human intracranial neoplasms.

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Year:  1979        PMID： 520822      PMCID： PMC1214065     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  9 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 2.  Pharmacogenetics: a possible pragmatic perspective in neoplasm predictability.

Authors:  S A Atlas; D W Nebert
Journal:  Semin Oncol       Date:  1978-03       Impact factor: 4.929

3.  Cytochrome P-450 and NADPH cytochrome c reductase in rat brain: formation of catechols and reactive catechol metabolites.

Authors:  H A Sasame; M M Ames; S D Nelson
Journal:  Biochem Biophys Res Commun       Date:  1977-10-10       Impact factor: 3.575

4.  Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.

Authors:  A Poland; E Glover
Journal:  Mol Pharmacol       Date:  1974-03       Impact factor: 4.436

5.  Genetic differences in microsomal electron transport: the Ah locus.

Authors:  D W Nebert
Journal:  Methods Enzymol       Date:  1978       Impact factor: 1.600

6.  Induction and suppression of hepatic and extrahepatic microsomal foreign-compound-metabolizing enzyme systems by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Authors:  G E Hook; J K Haseman; G W Lucier
Journal:  Chem Biol Interact       Date:  1975-03       Impact factor: 5.192

7.  Effect of charcoal-broiled beef on phenacetin metabolism in man.

Authors:  E J Pantuck; K C Hsiao; A H Conney; W A Garland; A Kappas; K E Anderson; A P Alvares
Journal:  Science       Date:  1976-12-03       Impact factor: 47.728

8.  Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).

Authors:  D R Bickers; A Kappas; A P Alvares
Journal:  J Pharmacol Exp Ther       Date:  1974-02       Impact factor: 4.030

9.  On the occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in rat brain.

Authors:  J A Cohn; A P Alvares; A Kappas
Journal:  J Exp Med       Date:  1977-06-01       Impact factor: 14.307
  9 in total
  1 in total

1.  Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction.

Authors:  A V Hodgson; T B White; J W White; H W Strobel
Journal:  Mol Cell Biochem       Date:  1993-03-24       Impact factor: 3.396
  1 in total

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