Literature DB >> 509782

Age-related changes in human thymus.

J Singh, A K Singh.   

Abstract

Thymic biopsies obtained during open heart surgery were examined for age-related involution of the parenchyma and changes in cell surface characteristics. In parallel with the parenchymal atrophy, E-rosette-forming cells continuously decreased with age and were progressively replaced by an increasing proportion of 'null' lymphoid cells. These changes appeared to be independent of each other. The significance of these findings in the context of the host's immune mechanism is discussed.

Entities:  

Mesh：

Year:  1979        PMID： 509782      PMCID： PMC1537774     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  11 in total

1.  In vitro differentiation of human marrow cells into T lymphocytes by thymic extracts using the rosette technique.

Authors:  G S Incefy; P L'Esperance; R A Good
Journal:  Clin Exp Immunol       Date:  1975-03       Impact factor: 4.330

2.  Regulation of theta-antigen expression by agents altering cyclic AMP level and by thymic factor.

Authors:  M A Bach; C Fournier; J F Bach
Journal:  Ann N Y Acad Sci       Date:  1975-02-28       Impact factor: 5.691

3.  Age involution in the normal human adult thymus.

Authors:  J G Simpson; E S Gray; J S Beck
Journal:  Clin Exp Immunol       Date:  1975-02       Impact factor: 4.330

4.  Age, thymic involution, and circulating thymic hormone activity.

Authors:  V M Lewis; J J Twomey; P Bealmear; G Goldstein; R A Good
Journal:  J Clin Endocrinol Metab       Date:  1978-07       Impact factor: 5.958

5.  Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy.

Authors:  J W Kappler; P C Hunter; D Jacobs; E Lord
Journal:  J Immunol       Date:  1974-07       Impact factor: 5.422

6.  Isolation of normal T cells in chronic lymphatic leukaemia.

Authors:  J Wybran; S Chantler; H H Fudenberg
Journal:  Lancet       Date:  1973-01-20       Impact factor: 79.321

7.  Immunoglobulins on the surface of human lymphocytes.

Authors:  M Papamichail; J C Brown; E J Holborow
Journal:  Lancet       Date:  1971-10-16       Impact factor: 79.321

8.  Antigen-binding lymphocytes in human fetal thymus.

Authors:  J M Dwyer; I R Mackay
Journal:  Lancet       Date:  1970-06-06       Impact factor: 79.321

9.  Ontogeny of the human lymphoid system: study of the cytological maturation and the incorporation of tritiated thymidine and uridine in the foetal thymus and lymph node and in the infantile thymus.

Authors:  M Papiernik
Journal:  J Cell Physiol       Date:  1972-10       Impact factor: 6.384

10.  Rosette formation by human thymocytes.

Authors:  S Whittingham; I R Mackay
Journal:  Cell Immunol       Date:  1973-03       Impact factor: 4.868
View more
  10 in total

1.  Indirect demonstration of the lifetime function of human thymus.

Authors:  M Marusić; M Turkalj-Kljajić; M Petrovecki; B Uzarević; M Rudolf; D Batinić; R Ugljen; D Anić; Z Cavar; I Jelić; B Malenica
Journal:  Clin Exp Immunol       Date:  1998-02       Impact factor: 4.330

2.  Altered cellular response to UV irradiation in a patient affected by premature ageing.

Authors:  M Stefanini; G Orecchia; G Rabbiosi; F Nuzzo
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132

3.  Production of auto-anti-idiotype antibody during the normal immune response. XIV. Evidence for the antigen-independent operation of the idiotype network.

Authors:  Y T Kim; T Deblasio; G J Thorbecke; M E Weksler; G W Siskind
Journal:  Immunology       Date:  1989-06       Impact factor: 7.397

4.  The human thymus in ageing: histologic involution paralleled by increased mitogen response and by enrichment of OKT3+ lymphocytes.

Authors:  C D Baroni; M Valtieri; A Stoppacciaro; L P Ruco; S Uccini; C Ricci
Journal:  Immunology       Date:  1983-12       Impact factor: 7.397

5.  Reversal of ageing changes in the thymus of rats by chemical or surgical castration.

Authors:  M D Kendall; F T Fitzpatrick; B D Greenstein; F Khoylou; B Safieh; A Hamblin
Journal:  Cell Tissue Res       Date:  1990-09       Impact factor: 5.249

6.  Effect of thymosin on glucocorticoid receptor activity and glucocorticoid sensitivity of human thymocytes.

Authors:  D D Ma; A H Ho; A V Hoffbrand
Journal:  Clin Exp Immunol       Date:  1984-02       Impact factor: 4.330

7.  Involution patterns of the human thymus. I Size of the cortical area as a function of age.

Authors:  P Tosi; R Kraft; P Luzi; M Cintorino; G Fankhauser; M W Hess; H Cottier
Journal:  Clin Exp Immunol       Date:  1982-02       Impact factor: 4.330

8.  Autoantibodies to a regulatory T cell subset in human ageing.

Authors:  A J Strelkauskas; J A Andrew; E J Yunis
Journal:  Clin Exp Immunol       Date:  1981-08       Impact factor: 4.330

Review 9.  Stress, ageing and their influence on functional, cellular and molecular aspects of the immune system.

Authors:  Ana Vitlic; Janet M Lord; Anna C Phillips
Journal:  Age (Dordr)       Date:  2014-02-25

10.  Age Difference in Morphology and Immunohistology inthe Thymus and Spleen in Crl:CD (SD) Rats.

Authors:  Rinya Kodama; Takanobu Okazaki; Tamio Sato; Shuichiro Iwashige; Yohei Tanigawa; Junko Fujishima; Akiko Moriyama; Nobuyoshi Yamashita; Yuji Sasaki; Tsuyoshi Yoshikawa; Yasuhiro Kamimura; Hiroshi Maeda
Journal:  J Toxicol Pathol       Date:  2012-03       Impact factor: 1.628
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.