Literature DB >> 5078252

Aryl hydrocarbon hydroxylase induction in human leukocytes.

D L Busbee, C R Shaw, E T Cantrell.   

Abstract

A method for determining aryl hydrocarbon hydroxylase induction in human leukocytes is described. Leukocytes from healthy volunteers were cultured in the presence of phytohemagglutinin, a mitogen. Addition of 3-methylcholanthrene to 72-hour cultures induced a fourfold increase in aryl hydroxylase activity. In the absence of a mitogenic agent, 3-methylcholanthrene stimulation of increased enzymatic activity did not occur.

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Year:  1972        PMID： 5078252     DOI： 10.1126/science.178.4058.315

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  Induction of 16alpha-hydroxylase in cultured human lymphocytes.

Authors:  I E Muijsson; M L Coomes; E T Cantrell; D E Anderson; D L Busbee
Journal:  Biochem Genet       Date:  1975-08       Impact factor: 1.890

2.  Comparison of aryl hydrocarbon hydroxylase induction in cultured blood lymphocytes and pulmonary macrophages.

Authors:  T L McLemore; R R Martin; K L Toppell; D L Busbee; E T Cantrell
Journal:  J Clin Invest       Date:  1977-11       Impact factor: 14.808

3.  Hydrocarbon-metabolizing activity of various mammalian cells in culture.

Authors:  R E Kouri; R Kiefer; E M Zimmerman
Journal:  In Vitro       Date:  1974 Jul-Aug

4.  Genetic variation of aryl hydrocarbon hydroxylase in human lymphocytes.

Authors:  G Kellermann; M Luyten-Kellermann; C R Shaw
Journal:  Am J Hum Genet       Date:  1973-05       Impact factor: 11.025

5.  Variation in individual responses to the cytotoxicity of cigarette smoke.

Authors:  J M Hopkin; C M Steel
Journal:  Thorax       Date:  1980-10       Impact factor: 9.139

6.  Leucoplakia of the oral cavity, smoking and arylhydrocarbon-hydroxylase inducibility.

Authors:  L Andréasson; G Björlin; R Korsgaard; I Mattiasson; E Trell; L Trell
Journal:  Postgrad Med J       Date:  1982-03       Impact factor: 2.401

7.  Glutathione S-transferase in human lymphoid cell lines and fractionated peripheral leucocytes.

Authors:  N Kaplowitz; C Spina; M Graham; J Kuhlenkamp
Journal:  Biochem J       Date:  1978-03-01       Impact factor: 3.857

8.  Inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes: a study of repeatability.

Authors:  K A Fletcher; D A Evans; M V Canning
Journal:  J Med Genet       Date:  1978-06       Impact factor: 6.318

9.  Aryl hydrocarbon hydroxylase activity in pulmonary alveolar macrophages and lymphocytes from lung cancer and noncancer patients: a correlation with family histories of cancer.

Authors:  T L McLemore; R R Martin; R R Springer; N Wray; E T Cantrell; D L Busbee
Journal:  Biochem Genet       Date:  1979-10       Impact factor: 1.890

10.  Induction of aryl hydrocarbon hydroxylase in human pulmonary alveolar macrophages by cigarette smoking.

Authors:  E T Cantrell; G A Warr; D L Busbee; R R Martin
Journal:  J Clin Invest       Date:  1973-08       Impact factor: 14.808
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