Literature DB >> 5077915

Latent osteomalacia in epileptic patients on anticonvulsants.

C Christiansen, M Kristensen, P Rodbro.   

Abstract

The bone mineral content was measured in 10 epileptic patients on long-term treatment with phenytoin before and during treatment with vitamin D. None of the patients showed biochemical signs of osteomalacia. Initially subnormal values for bone mineral content were found, which increased significantly during treatment. The results suggest the occurrence of latent osteomalacia in a fairly high proportion of epileptic patients on anticonvulsants.

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Year:  1972        PMID： 5077915      PMCID： PMC1788670          DOI： 10.1136/bmj.3.5829.738

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  6 in total

1.  The mineral content in bone. Measured by means of 27.5 keV radiation from 125I.

Authors:  H Jensen; C Christiansen; I F Lindbjerg; O Munck
Journal:  Acta Radiol Suppl       Date:  1972

2.  25-hydroxycholecalciferol. The probable metabolically active form of vitamin D3: its identification and subcellular site of action.

Authors:  H F DeLuca
Journal:  Arch Intern Med       Date:  1969-10

3.  Rapid determination of serum diphenylhydantoin by gas chromatography.

Authors:  N E Larsen
Journal:  Med Lab Technol       Date:  1971-10

4.  Bone density in patients receiving long-term anticonvulsant therapy.

Authors:  J Linde; J Molholm Hansen; K Siersbaek-Nielsen; V Fuglsang-Fredriksen
Journal:  Acta Neurol Scand       Date:  1971       Impact factor: 3.209

5.  Precision and accuracy of bone mineral determination by direct photon absorptiometry.

Authors:  J R Cameron; R B Mazess; J A Sorenson
Journal:  Invest Radiol       Date:  1968 May-Jun       Impact factor: 6.016

6.  Altered calcium metabolism in epileptic children on anticonvulsants.

Authors:  J Hunter; J D Maxwell; D A Stewart; V Parsons; R Williams
Journal:  Br Med J       Date:  1971-10-23
  6 in total
  9 in total

1.  Bone mineral content in epileptics.

Authors:  L Lidgren; B E Nilsson; A Wallöe
Journal:  Calcif Tissue Int       Date:  1979-10-31       Impact factor: 4.333

2.  Effects of anticonvulsants and inactivity on bone disease in epileptics.

Authors:  L E Murchison; P D Bewsher; M Chesters; J Gilbert; G Catto; E Law; E McKay; H S Ross
Journal:  Postgrad Med J       Date:  1975-01       Impact factor: 2.401

3.  Anticonvulsant osteomalacia.

Authors: 
Journal:  Br Med J       Date:  1976-12-04

4.  Effect of vitamin D on bone mineral mass in normal subjects and in epileptic patients on anticonvulsants: a controlled therapeutic trial.

Authors:  C Christiansen; P Rodbro; M Lund
Journal:  Br Med J       Date:  1973-04-28

5.  Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.

Authors:  C Christiansen; P Rodbro; M Lund
Journal:  Br Med J       Date:  1973-12-22

Review 6.  Anti-epileptic medication and bone health.

Authors:  S J Petty; T J O'Brien; J D Wark
Journal:  Osteoporos Int       Date:  2006-11-08       Impact factor: 4.507

7.  [The frequency of adult anticonvulsant osteomalacia in relation to duration of therapy and dosage of anticonvulsants (author's transl)].

Authors:  U Mehregan; K H Krause; P Prager
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1979-04-12

8.  Effects of anticonvulsants and methotrexate on calcium disposition.

Authors:  M A Evans
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980       Impact factor: 3.000

9.  Phenytoin inhibition of parathyroid hormone induced bone resorption in vitro.

Authors:  M Harris; M V Jenkins; M R Wills
Journal:  Br J Pharmacol       Date:  1974-03       Impact factor: 8.739
  9 in total

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