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Literature DB >> 5064226

Cell surface immunoglobulin. IV. Distribution among thymocytes, bone mrrow cells, and their derived populations.

E S Vitetta, C Bianco, V Nussenzweig, J W Uhr.

Abstract

Thymocytes, bone marrow cells, and their derived T and B cell populations were examined for the presence of Ig by the cell surface radioiodination technique. Both IgM and IgG were identified on bone marrow cells. Thymocytes and T cells had no detectable cell surface Ig. Radiolabeling of mixtures of B cells and thymocytes suggest that the method may detect as little as 250 molecules of Ig per cell. Based on these findings, we suggest that the T cell receptor for antigen is not a conventional tetrameric Ig.

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Year: 1972 PMID： 5064226 PMCID： PMC2139194 DOI： 10.1084/jem.136.1.81

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

30 in total

1. Hydrocortisne resistance of graft vs host activity in mouse thymus, spleen and bone marrow.

Authors: J J Cohen; M Fschbach; H N Claman
Journal: J Immunol Date: 1970-11 Impact factor: 5.422

2. Antigen-binding lymphocytes in human fetal thymus.

Authors: J M Dwyer; I R Mackay
Journal: Lancet Date: 1970-06-06 Impact factor: 79.321

3. Blocking of the lymphocyte antigen receptor site with anti-immunoglobulin sera in vitro.

Authors: N L Warner; P Byrt; G L Ada
Journal: Nature Date: 1970-06-06 Impact factor: 49.962

4. Immunoglobulin determinants on the surface of mouse lymphoid cells.

Authors: M C Raff; M Sternberg; R B Taylor
Journal: Nature Date: 1970-02-07 Impact factor: 49.962

5. Antigen-binding cells in normal mouse thymus.

Authors: F Modabber; S Morikawa; A H Coons
Journal: Science Date: 1970-12-04 Impact factor: 47.728

6. Two distinct populations of peripheral lymphocytes in mice distinguishable by immunofluorescence.

Authors: M C Raff
Journal: Immunology Date: 1970-10 Impact factor: 7.397

7. Surface immunoglobulin-moieties on lymphoid cells.

Authors: E Klein; T Eskeland; M Inoue; R Strom; B Johansson
Journal: Exp Cell Res Date: 1970-09 Impact factor: 3.905

8. Immunoglobulins on the surface of lymphocytes. I. Distribution and quantitation.

Authors: E Rabellino; S Colon; H M Grey; E R Unanue
Journal: J Exp Med Date: 1971-01-01 Impact factor: 14.307

9. Immunoglobulin spots on the surface of rabbit lymphocytes.

Authors: B Pernis; L Forni; L Amante
Journal: J Exp Med Date: 1970-11 Impact factor: 14.307

10. A population of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes. I. Separation and characterization.

Authors: C Bianco; R Patrick; V Nussenzweig
Journal: J Exp Med Date: 1970-10-01 Impact factor: 14.307

36 in total

1. The lymphocyte plasma membrane: locus of control in the immune response.

Authors: L M Jerry; A K Sullivan
Journal: In Vitro Date: 1976-03

2. Demonstration of immunoglobulin on the surface of thymus lymphocytes.

Authors: V Santana; N Wedderburn; J L Turk
Journal: Immunology Date: 1974-07 Impact factor: 7.397

3. Surface proteins of thymus-derived lymphocytes and bone-marrow-derived lymphocytes. Selective isolation of immunoglobulin and the theta-antigen by non-ionic detergents.

Authors: R E Cone; J J Marchalonis
Journal: Biochem J Date: 1974-06 Impact factor: 3.857

Cell surface immunoglobulin. IV. Distribution among thymocytes, bone mrrow cells, and their derived populations.

1. Hydrocortisne resistance of graft vs host activity in mouse thymus, spleen and bone marrow.

2. Antigen-binding lymphocytes in human fetal thymus.

3. Blocking of the lymphocyte antigen receptor site with anti-immunoglobulin sera in vitro.

4. Immunoglobulin determinants on the surface of mouse lymphoid cells.

5. Antigen-binding cells in normal mouse thymus.

6. Two distinct populations of peripheral lymphocytes in mice distinguishable by immunofluorescence.

7. Surface immunoglobulin-moieties on lymphoid cells.

8. Immunoglobulins on the surface of lymphocytes. I. Distribution and quantitation.

9. Immunoglobulin spots on the surface of rabbit lymphocytes.

10. A population of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes. I. Separation and characterization.

1. The lymphocyte plasma membrane: locus of control in the immune response.

2. Demonstration of immunoglobulin on the surface of thymus lymphocytes.

3. Surface proteins of thymus-derived lymphocytes and bone-marrow-derived lymphocytes. Selective isolation of immunoglobulin and the theta-antigen by non-ionic detergents.

4. Antibody against Ir-region controlled antigen in mice.

5. The functions of immune T and B rosette-forming cells.

6. Receptors for IgM on murine lymphoid cells.

7. Sequences related to immunoglobulin kappa chain messenger RNA in T cells.

8. The Ly-3 antigens on mouse thymocytes: immune precipitation and molecular weight characterization.

9. Lymphocyte receptors. II. Receptors for rabbit IgM on human T lymphocytes.

10. Surface immunoglobulin on activated human peripheral blood thymus-derived cells.