Literature DB >> 4920186

Antigen-binding cells in normal mouse thymus.

F Modabber, S Morikawa, A H Coons.   

Abstract

The thymus of a normal adult mouse contains lymphocytic cells with a large number of antigen-binding receptors. Binding of the antigen by these cells is specific and can be inhibited by cross-reactive materials. It is possible that the interaction of thymocytes with antibody-forming precursor cells, required in the primary immune response to certain antigens, is mediated by these specific antigen-binding cells of the thymus.

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Year:  1970        PMID： 4920186     DOI： 10.1126/science.170.3962.1102

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Immunosuppressive activity of BCG: effects of adjuvant disease, lymphocyte subpopulations, and homing of thoracic duct cells in rats.

Authors:  R I Sutherland; M A Spadaro-Antonelli; V J Lawrence; F Quagliata
Journal:  Infect Immun       Date:  1979-07       Impact factor: 3.441

2.  Rosette formation by mouse lymphocytes. I. Demonstration by indirect immunofluorescence of T cells binding sheep erythrocytes.

Authors:  M I Gyöngyössy; J H Playfair
Journal:  Clin Exp Immunol       Date:  1974-10       Impact factor: 4.330

3.  Suppression of adjuvant disease by bacillus Calmette-Guérin (BCG).

Authors:  R I Sutherland; F Quagliata
Journal:  Experientia       Date:  1975-03-15

4.  Binding of antigen-enzyme complex by antigen-binding cells as an approach for immunogdiagnosis.

Authors:  F Z Modabber; G M Bahr
Journal:  Infect Immun       Date:  1979-01       Impact factor: 3.441

5.  The distribution of 51Cr-labeled lymphocytes into antigen-stimulated mice. Lymphocyte trapping.

Authors:  M M Zatz; E M Lance
Journal:  J Exp Med       Date:  1971-07-01       Impact factor: 14.307

6.  Immunoglobulin synthesis and secretion by cells in the mouse thymus that do not bear theta antigen.

Authors:  E S Vitetta; J W Uhr; E A Boyse
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

7.  Specific binding of peroxidase-labeled myelin basic protein in allergic encephalomyelitis.

Authors:  A B Johnson; H M Wiśniewski; C S Raine; E H Eylar; R D Terry
Journal:  Proc Natl Acad Sci U S A       Date:  1971-11       Impact factor: 11.205

8.  Studies on membrane-bound receptors for antigen. Preparation of populations of receptor-depleted lymphocytes.

Authors:  R D Stout; A H Coons
Journal:  J Exp Med       Date:  1973-10-01       Impact factor: 14.307

9.  Cell surface immunoglobulin. IV. Distribution among thymocytes, bone mrrow cells, and their derived populations.

Authors:  E S Vitetta; C Bianco; V Nussenzweig; J W Uhr
Journal:  J Exp Med       Date:  1972-07-01       Impact factor: 14.307

10.  Stimulation of antibody production to the hapten 2,4-dinitrobenzene by affinity labeled murine lymphoid cells. I. Ability of affinity labeled murine lymphoid cells to activate the in vivo immune response.

Authors:  D A Lawrence; W O Weigle
Journal:  J Exp Med       Date:  1974-04-01       Impact factor: 14.307
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