Literature DB >> 505005

A glucose-controlled insulin-delivery system: semisynthetic insulin bound to lectin.

M Brownlee, A Cerami.   

Abstract

A stable, biologically active glycosylated insulin derivative that is complementary to the major combining site of concanavalin A has been synthesized. Hormone release is proportional to the quantity of glucose present. Glucose regulation of exogenous insulin delivery could have important applications in the therapy of diabetes mellitus.

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Year:  1979        PMID: 505005     DOI: 10.1126/science.505005

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  56 in total

Review 1.  Optimisation of treatment by applying programmable rate-controlled drug delivery technology.

Authors:  Yie W Chien; Senshang Lin
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  Insulin analogs for the treatment of diabetes mellitus: therapeutic applications of protein engineering.

Authors:  Daniel F Berenson; Allison R Weiss; Zhu-Li Wan; Michael A Weiss
Journal:  Ann N Y Acad Sci       Date:  2012-03-13       Impact factor: 5.691

Review 3.  Advances in Biomaterials for Drug Delivery.

Authors:  Owen S Fenton; Katy N Olafson; Padmini S Pillai; Michael J Mitchell; Robert Langer
Journal:  Adv Mater       Date:  2018-05-07       Impact factor: 30.849

Review 4.  Glucose-Responsive Insulin and Delivery Systems: Innovation and Translation.

Authors:  Jinqiang Wang; Zejun Wang; Jicheng Yu; Anna R Kahkoska; John B Buse; Zhen Gu
Journal:  Adv Mater       Date:  2019-08-18       Impact factor: 30.849

Review 5.  Glucose-responsive insulin release: Analysis of mechanisms, formulations, and evaluation criteria.

Authors:  Jianhai Yang; Zhiqiang Cao
Journal:  J Control Release       Date:  2017-01-31       Impact factor: 9.776

Review 6.  Development of glucose-responsive 'smart' insulin systems.

Authors:  Nischay K Rege; Nelson F B Phillips; Michael A Weiss
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2017-08       Impact factor: 3.243

Review 7.  Programmable hydrogels.

Authors:  Yong Wang
Journal:  Biomaterials       Date:  2018-03-05       Impact factor: 12.479

8.  Engineering Synthetically Modified Insulin for Glucose-Responsive Diabetes Therapy.

Authors:  Matthew J Webber; Daniel G Anderson; Robert Langer
Journal:  Expert Rev Endocrinol Metab       Date:  2015-07-18

9.  In vitro release dynamics of insulin from a loaded hydrophilic polymeric network.

Authors:  A K Bajpai; Smitha Bhanu
Journal:  J Mater Sci Mater Med       Date:  2004-01       Impact factor: 3.896

10.  Glucose-sensing pulmonary delivery of human insulin to the systemic circulation of rats.

Authors:  Efstathios Karathanasis; Rohan Bhavane; Ananth V Annapragada
Journal:  Int J Nanomedicine       Date:  2007
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