Literature DB >> 499290

One hundred digitalis blood levels. A utilization review.

W B Hladik, C A Dujovne.   

Abstract

One hundred consecutive digitalis serum level determination requests and results were analyzed to evaluate the rational of ordering the test and utilizing the results at his hospital. Sixty-six percent of the reasons given for ordering the test were categorized as "acceptable". As many as 25% of physicians requesting the test considered digitalis levels as "routine" diagnostic tests in a patient taking these drugs. There were 12 levels within the potentially toxic range, 19 below the usual therapeutic range. The physicians modified their therapeutic management in 38 patients as a result of their knowledge of the digitalis level in blood. It is concluded that digitalis level determinations at this hospital are reasonably well utilized and that knowledge of the digitalis levels improve the accuracy of digitalis utilization in at least one third of the patients in whom this test is done.

Entities:  

Mesh:

Substances:

Year:  1979        PMID: 499290     DOI: 10.1007/bf00561740

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  20 in total

1.  Association between clinical cardiac status, laboratory parameters, and digoxin usage.

Authors:  D H Huffman; J W Crow; P Pentikäinen; D L Azarnoff
Journal:  Am Heart J       Date:  1976-01       Impact factor: 4.749

2.  The serum digitalis concentration--does it diagnose digitalis toxicity?

Authors:  J A Ingelfinger; P Goldman
Journal:  N Engl J Med       Date:  1976-04-15       Impact factor: 91.245

3.  Plasma digoxin concentrations in patients on admission to hospital.

Authors:  S G Carruthers; J G Kelly; D G McDevitt
Journal:  Br Heart J       Date:  1974-07

4.  Absorption of orally given digoxin preparations.

Authors:  D H Huffman; D L Azarnoff
Journal:  JAMA       Date:  1972-11-20       Impact factor: 56.272

5.  Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay.

Authors:  T W Smith; V P Butler; E Haber
Journal:  N Engl J Med       Date:  1969-11-27       Impact factor: 91.245

6.  Plasma digoxin concentrations and digoxin toxicity in hospital patients.

Authors:  D C Evered; C Chapman
Journal:  Br Heart J       Date:  1971-07

Review 7.  Digitalis toxicity: epidemiology and clinical use of serum concentration measurements.

Authors:  T W Smith
Journal:  Am J Med       Date:  1975-04       Impact factor: 4.965

Review 8.  Clinical use of digitalis glycosides.

Authors:  D H Huffman
Journal:  Am J Hosp Pharm       Date:  1976-02

9.  Reduction of digoxin toxicity associated with measurement of serum levels. A report from the Boston Collaborative Drug Surveillance Program.

Authors:  D W Duhme; D J Greenblatt; J Koch-Weser
Journal:  Ann Intern Med       Date:  1974-04       Impact factor: 25.391

10.  Everest MS: Measurement of digoxin in plasma and its use in diagnosis of digoxin intoxication.

Authors:  D G Grahame-Smith
Journal:  Br Med J       Date:  1969-02-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.