Literature DB >> 4977283

Human immunity to the meningococcus. IV. Immunogenicity of group A and group C meningococcal polysaccharides in human volunteers.

E C Gotschlich, I Goldschneider, M S Artenstein.   

Abstract

High molecular weight group A and group C meningococcal polysaccharides had no significant toxicity for mice or guinea pigs. Furthermore, these polysaccharide preparations contained negligible amounts of biologically active endotoxin. The high molecular weight group A and group C meningococcal polysaccharides were excellent immunogens in six human volunteers. Antibodies belonging to the immunoglobulin classes IgG, IgM, and IgA were produced. These antibodies were highly meningococcocidal in the presence of complement.

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Year:  1969        PMID： 4977283      PMCID： PMC2138657          DOI： 10.1084/jem.129.6.1367

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  17 in total

1.  The effect of variation in molecular weight on the antigenicity of dextran in man.

Authors:  E A KABAT; A E BEZER
Journal:  Arch Biochem Biophys       Date:  1958-12       Impact factor: 4.013

2.  The specific hapten of group C (group II alpha) meningococcus. I. Preparation and immunological behavior.

Authors:  R G WATSON; H W SCHERP
Journal:  J Immunol       Date:  1958-10       Impact factor: 5.422

3.  Studies on the mechanism of the immunological paralysis induced in mice by pneumococcal polysaccharides.

Authors:  L D FELTON; G KAUFFMANN; B PRESCOTT; B OTTINGER
Journal:  J Immunol       Date:  1955-01       Impact factor: 5.422

4.  EXPERIMENTAL MENINGOCOCCAL INFECTION IN MICE.

Authors:  C P Miller
Journal:  Science       Date:  1933-10-13       Impact factor: 47.728

5.  PERTUSSIS VACCINE TESTING FOR FREEDOM-FROM-TOXICITY.

Authors:  M PITTMAN; C B COX
Journal:  Appl Microbiol       Date:  1965-05

6.  STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI.

Authors:  H W Scherp; G Rake
Journal:  J Exp Med       Date:  1945-01-01       Impact factor: 14.307

7.  Human immunity to the meningococcus. II. Development of natural immunity.

Authors:  I Goldschneider; E C Gotschlich; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307

8.  Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharides.

Authors:  E C Gotschlich; T Y Liu; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307

9.  Human immunity to the meningococcus. I. The role of humoral antibodies.

Authors:  I Goldschneider; E C Gotschlich; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307

10.  The effect of bacterial endotoxins on the water intake and body weight of mice.

Authors:  R J DUBOS; R W SCHAEDLER
Journal:  J Exp Med       Date:  1961-05-01       Impact factor: 14.307
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  124 in total

1.  Opsonophagocytosis of fluorescent polystyrene beads coupled to Neisseria meningitidis serogroup A, C, Y, or W135 polysaccharide correlates with serum bactericidal activity.

Authors:  Joseph Martinez; Tamara Pilishvili; Suzanne Barnard; Joseph Caba; Willie Spear; Sandra Romero-Steiner; George M Carlone
Journal:  Clin Diagn Lab Immunol       Date:  2002-03

Review 2.  Francisella tularensis--a model for studies of the immune response to intracellular bacteria in man.

Authors:  A Tärnvik; M Eriksson; G Sandström; A Sjöstedt
Journal:  Immunology       Date:  1992-07       Impact factor: 7.397

3.  Structural bioinformatics of Neisseria meningitidis LD-carboxypeptidase: implications for substrate binding and specificity.

Authors:  Yasmeen Rashid; M Kamran Azim
Journal:  Protein J       Date:  2011-12       Impact factor: 2.371

4.  A universal vaccine for serogroup B meningococcus.

Authors:  Marzia M Giuliani; Jeannette Adu-Bobie; Maurizio Comanducci; Beatrice Aricò; Silvana Savino; Laura Santini; Brunella Brunelli; Stefania Bambini; Alessia Biolchi; Barbara Capecchi; Elena Cartocci; Laura Ciucchi; Federica Di Marcello; Francesca Ferlicca; Barbara Galli; Enrico Luzzi; Vega Masignani; Davide Serruto; Daniele Veggi; Mario Contorni; Maurizio Morandi; Alessandro Bartalesi; Vanda Cinotti; Donatella Mannucci; Francesca Titta; Elisa Ovidi; Jo Anne Welsch; Dan Granoff; Rino Rappuoli; Mariagrazia Pizza
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-06       Impact factor: 11.205

Review 5.  Prospects for vaccine prevention of meningococcal infection.

Authors:  Lee H Harrison
Journal:  Clin Microbiol Rev       Date:  2006-01       Impact factor: 26.132

6.  Preparation of human hyperimmune globulin to Haemophilus influenzae b, Streptococcus pneumoniae, and Neisseria meningitidis.

Authors:  G R Siber; D M Ambrosino; J McIver; T J Ervin; G Schiffman; S Sallan; G F Grady
Journal:  Infect Immun       Date:  1984-07       Impact factor: 3.441

7.  Comparison of radioimmunoassay and enzyme-linked immunosorbent assay in measurement of antibodies to Neisseria meningitidis group A capsular polysaccharide.

Authors:  E C Beuvery; M H Kayhty; A B Leussink; V Kanhai
Journal:  J Clin Microbiol       Date:  1984-10       Impact factor: 5.948

Review 8.  Meningococcal vaccines.

Authors:  Jens U Rüggeberg; Andrew J Pollard
Journal:  Paediatr Drugs       Date:  2004       Impact factor: 3.022

9.  Meningococcal infections. 5. Duration of polysaccharide-vaccine-induced antibody.

Authors:  M S Artenstein
Journal:  Bull World Health Organ       Date:  1971       Impact factor: 9.408

10.  The relationship between group A and group C meningococcal polysaccharides and serum opsonins in man.

Authors:  R B Roberts
Journal:  J Exp Med       Date:  1970-03-01       Impact factor: 14.307
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