Literature DB >> 11874898

Opsonophagocytosis of fluorescent polystyrene beads coupled to Neisseria meningitidis serogroup A, C, Y, or W135 polysaccharide correlates with serum bactericidal activity.

Joseph Martinez1, Tamara Pilishvili, Suzanne Barnard, Joseph Caba, Willie Spear, Sandra Romero-Steiner, George M Carlone.   

Abstract

We developed a polysaccharide-specific flow cytometric opsonophagocytic assay (OPA) for the simultaneous measurement of functional antibody to Neisseria meningitidis serogroups A, C, Y, and W135. OPA titers significantly correlated with serum bactericidal assay titers for all serogroups tested (mean r = 0.96; P < 0.001). OPA could be used in meningococcal vaccine evaluation.

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Year:  2002        PMID： 11874898      PMCID： PMC119948          DOI： 10.1128/cdli.9.2.485-488.2002

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  23 in total

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5.  Ex vivo bactericidal activity against group C Neisseria meningitidis in seronegative subjects.

Authors:  M L Gómez-Lus; L Aguilar; J Vázquez; M J Giménez; G Ruiz; S Berrón; F Fuentes; J Prieto
Journal:  Infection       Date:  2000-09       Impact factor: 3.553

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Authors:  R B Roberts
Journal:  J Exp Med       Date:  1970-03-01       Impact factor: 14.307

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Journal:  J Clin Invest       Date:  1980-08       Impact factor: 14.808

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Authors:  L F Smith; G H Lowell
Journal:  J Infect Dis       Date:  1980-06       Impact factor: 5.226

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Authors:  E C Gotschlich; I Goldschneider; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307

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Authors:  I Goldschneider; E C Gotschlich; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307
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  7 in total

1.  Evaluation of multiplex flow cytometric opsonophagocytic assays for determination of functional anticapsular antibodies to Streptococcus pneumoniae.

Authors:  Joseph E Martinez; Elizabeth A Clutterbuck; Han Li; Sandra Romero-Steiner; George M Carlone
Journal:  Clin Vaccine Immunol       Date:  2006-04

2.  Immunization with live Neisseria lactamica protects mice against meningococcal challenge and can elicit serum bactericidal antibodies.

Authors:  Yanwen Li; Qian Zhang; Megan Winterbotham; Eva Mowe; Andrew Gorringe; Christoph M Tang
Journal:  Infect Immun       Date:  2006-09-11       Impact factor: 3.441

3.  Naturally acquired passive protective activity against Neisseria meningitidis Group C in the absence of serum bactericidal activity.

Authors:  Jo Anne Welsch; Dan Granoff
Journal:  Infect Immun       Date:  2004-10       Impact factor: 3.441

4.  Investigation of different group A immunoassays following one dose of meningococcal group A conjugate vaccine or A/C polysaccharide vaccine in adults.

Authors:  H Findlow; B D Plikaytis; A Aase; M C Bash; H Chadha; C Elie; G Laher; J Martinez; T Herstad; E Newton; S Viviani; C Papaspyridis; P Kulkarni; M Wilding; M P Preziosi; E Marchetti; M Hassan-King; F M La Force; G Carlone; R Borrow
Journal:  Clin Vaccine Immunol       Date:  2009-05-27

5.  Fully human monoclonal antibodies from antibody secreting cells after vaccination with Pneumovax®23 are serotype specific and facilitate opsonophagocytosis.

Authors:  Kenneth Smith; Jennifer J Muther; Angie L Duke; Emily McKee; Nai-Ying Zheng; Patrick C Wilson; Judith A James
Journal:  Immunobiology       Date:  2012-09-03       Impact factor: 3.144

6.  Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against Streptococcus pyogenes.

Authors:  Sanaz Salehi; Claudia M Hohn; Thomas A Penfound; James B Dale
Journal:  mSphere       Date:  2018-12-19       Impact factor: 4.389

7.  Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination.

Authors:  Zheng Quan Toh; Rachel A Higgins; Nadia Mazarakis; Elysia Abbott; Jordan Nathanielsz; Anne Balloch; Kim Mulholland; Paul V Licciardi
Journal:  Vaccines (Basel)       Date:  2021-06-20
  7 in total

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