Literature DB >> 4942762

Isolation and partial characterization of temperature-sensitive Escherichia coli mutants with altered leucyl- and seryl-transfer ribonucleic acid synthetases.

B Low, F Gates, T Goldstein, D Söll.   

Abstract

Two temperature-sensitive mutants of Escherichia coli have been found in which the conditional growth is a result of a thermosensitive leucyl-transfer ribonucleic acid (tRNA) synthetase and seryl-tRNA synthetase, respectively. The corresponding genetic loci, leuS and serS, cotransduce with lip and serC, respectively. As a result of the mutationally altered leucyl-tRNA synthetase, some leucine-, valine-, and isoleucine-forming enzymes were derepressed. Thus, leucyl-tRNA synthetase is involved in the repression of the enzymes needed for the synthesis of branched-chain amino acids.

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Year:  1971        PMID: 4942762      PMCID: PMC247134          DOI: 10.1128/jb.108.2.742-750.1971

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  35 in total

1.  The catalytic properties of tyrosyl ribonucleic acid synthetases from Escherichia coli and Bacillus subtilis.

Authors:  R Calendar; P Berg
Journal:  Biochemistry       Date:  1966-05       Impact factor: 3.162

2.  Isolation of the novel regulatory mutants of the tryptophan biosynthetic system in Escherichia coli.

Authors:  Y Kano; A Matsushiro; Y Shimura
Journal:  Mol Gen Genet       Date:  1968

3.  Biochemical and genetic studies with lysine+methionine mutants of Escherichia coli: lipoic acid and alpha-ketoglutarate dehydrogenase-less mutants.

Authors:  A A Herbert; J R Guest
Journal:  J Gen Microbiol       Date:  1968-10

4.  On the recognition of serine transfer RNA's specific for unrelated codons by the same seryl-transfer RNA synthetase.

Authors:  G Sundharadas; J R Katze; D Söll; W Konigsberg; P Lengyel
Journal:  Proc Natl Acad Sci U S A       Date:  1968-10       Impact factor: 11.205

5.  Selection of temperature-sensitive activating enzyme mutants in Escherichia coli.

Authors:  S Kaplan; D Anderson
Journal:  J Bacteriol       Date:  1968-03       Impact factor: 3.490

6.  [On the properties of a modified alanyl-t-RNA synthetase in a strain of escherichia coli with thermosensible growth].

Authors:  M Lazar; M Yaniv; F Gros
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1968-01-29

Review 7.  Roles of amino acid activating enzymes in cellular physiology.

Authors:  F C Neidhardt
Journal:  Bacteriol Rev       Date:  1966-12

8.  Histidine regulatory mutants in Salmonella typhimurium II. Histidine regulatory mutants having altered histidyl-tRNA synthetase.

Authors:  J R Roth; B N Ames
Journal:  J Mol Biol       Date:  1966-12-28       Impact factor: 5.469

9.  Mutants of Escherichia coli with an altered tryptophanyl-transfer ribonucleic acid synthetase.

Authors:  W F Doolittle; C Yanofsky
Journal:  J Bacteriol       Date:  1968-04       Impact factor: 3.490

10.  Isoleucine and valine metabolism of Escherichia coli. XV. Biochemical properties of mutants resistant to thiaisoleucine.

Authors:  A Szentirmai; M Szentirmai; H E Umbarger
Journal:  J Bacteriol       Date:  1968-05       Impact factor: 3.490

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  49 in total

1.  tRNA synthetase mutants of Escherichia coli K-12 are resistant to the gyrase inhibitor novobiocin.

Authors:  M Jovanovic; M Lilic; R Janjusevic; G Jovanovic; D J Savic; J Milija
Journal:  J Bacteriol       Date:  1999-05       Impact factor: 3.490

2.  Premature termination of in vivo transcription of a gene encoding a branched-chain amino acid transport protein in Escherichia coli.

Authors:  R M Williamson; D L Oxender
Journal:  J Bacteriol       Date:  1992-03       Impact factor: 3.490

3.  Construction of an ordered cosmid collection of the Escherichia coli K-12 W3110 chromosome.

Authors:  S Tabata; A Higashitani; M Takanami; K Akiyama; Y Kohara; Y Nishimura; A Nishimura; S Yasuda; Y Hirota
Journal:  J Bacteriol       Date:  1989-02       Impact factor: 3.490

4.  Amino acid toxicities of Escherichia coli that are prevented by leucyl-tRNA synthetase amino acid editing.

Authors:  Vrajesh A Karkhanis; Anjali P Mascarenhas; Susan A Martinis
Journal:  J Bacteriol       Date:  2007-09-21       Impact factor: 3.490

5.  Defects in transient tRNA translocation bypass tRNA synthetase quality control mechanisms.

Authors:  Rachel A Hellmann; Susan A Martinis
Journal:  J Biol Chem       Date:  2009-03-03       Impact factor: 5.157

6.  Molecular cloning, characterization and expression of cDNA encoding phosphoserine aminotransferase involved in phosphorylated pathway of serine biosynthesis from spinach.

Authors:  K Saito; Y Takagi; H C Ling; H Takahashi; M Noji
Journal:  Plant Mol Biol       Date:  1997-01       Impact factor: 4.076

Review 7.  Recalibrated linkage map of Escherichia coli K-12.

Authors:  B J Bachmann; K B Low; A L Taylor
Journal:  Bacteriol Rev       Date:  1976-03

8.  Transcription attenuation in Salmonella typhimurium: the significance of rare leucine codons in the leu leader.

Authors:  P W Carter; J M Bartkus; J M Calvo
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

9.  Penicillin-binding protein 2 inactivation in Escherichia coli results in cell division inhibition, which is relieved by FtsZ overexpression.

Authors:  D Vinella; D Joseleau-Petit; D Thévenet; P Bouloc; R D'Ari
Journal:  J Bacteriol       Date:  1993-10       Impact factor: 3.490

10.  Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli: structure of F100, F152, and F8 and mapping of the Escherichia coli chromosomal region fep-supE-gal-attlambda-uvrB.

Authors:  E Ohtsubo; M T Hsu
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

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