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Literature DB >> 4905675

Peptide chain termination. VI. Purification and site of action of S.

J Goldstein, G Milman, E Scolnick, T Caskey.

Abstract

PEPTIDE CHAIN TERMINATION IS A RESULT OF AT LEAST TWO EVENTS: terminator codon recognition and hydrolysis of peptidyl tRNA. A protein factor S, isolated from the supernatant of Escherichia coli B, stimulates fMet release. Factor S lowers the K(m) for terminator trinucleotides without altering the V(max) of release and therefore acts at terminator codon recognition. The S protein differs from initiation factors, elongation factor G, several forms of elongation factor T and release factors. The importance of the 2% Tu content in purified S is unresolved.

Entities: Chemical Species

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Year: 1970 PMID： 4905675 PMCID： PMC282921 DOI： 10.1073/pnas.65.2.430

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

11 in total

1. Translation of the genetic message, ii. Effect of initiation factors on the binding of formyl-methionyl-trna to ribosomes.

Authors: M Salas; M B Hille; J A Last; A J Wahba; S Ochoa
Journal: Proc Natl Acad Sci U S A Date: 1967-02 Impact factor: 11.205

2. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

3. Separation of three microbial amino acid polymerization factors.

Authors: J Lucas-Lenard; F Lipmann
Journal: Proc Natl Acad Sci U S A Date: 1966-06 Impact factor: 11.205

4. Translation of the genetic message. VII. Role of initiation factors in formation of the chain initiation complex with Escherichia coli ribosomes.

Authors: K Iwasaki; S Sabol; A J Wahba; S Ochoa
Journal: Arch Biochem Biophys Date: 1968-05 Impact factor: 4.013

5. Release factors differing in specificity for terminator codons.

Authors: E Scolnick; R Tompkins; T Caskey; M Nirenberg
Journal: Proc Natl Acad Sci U S A Date: 1968-10 Impact factor: 11.205

6. Peptide chain termination. 3. Stimulation of in vitro termination.

Authors: G Milman; J Goldstein; E Scolnick; T Caskey
Journal: Proc Natl Acad Sci U S A Date: 1969-05 Impact factor: 11.205

Review 7. Polypeptide chain elongation in protein biosynthesis.

Authors: F Lipmann
Journal: Science Date: 1969-05-30 Impact factor: 47.728

Review 8. Mechanism of protein biosynthesis.

Authors: P Lengyel; D Söll
Journal: Bacteriol Rev Date: 1969-06

9. Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomes.

Authors: J M Ravel
Journal: Proc Natl Acad Sci U S A Date: 1967-06 Impact factor: 11.205

10. Sequential translation of trinucleotide codons for the initiation and termination of protein synthesis.

Authors: C T Caskey; R Tompkins; E Scolnick; T Caryk; M Nirenberg
Journal: Science Date: 1968-10-04 Impact factor: 47.728

11 in total

1. Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex.

Authors: G Grentzmann; P J Kelly; S Laalami; M Shuda; M A Firpo; Y Cenatiempo; A Kaji
Journal: RNA Date: 1998-08 Impact factor: 4.942

2. Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3.

Authors: M Y Pavlov; D V Freistroffer; J MacDougall; R H Buckingham; M Ehrenberg
Journal: EMBO J Date: 1997-07-01 Impact factor: 11.598

3. The mechanism of tryptophan induction of tryptophanase operon expression: tryptophan inhibits release factor-mediated cleavage of TnaC-peptidyl-tRNA(Pro).

Authors: F Gong; K Ito; Y Nakamura; C Yanofsky
Journal: Proc Natl Acad Sci U S A Date: 2001-07-24 Impact factor: 11.205

Peptide chain termination. VI. Purification and site of action of S.

1. Translation of the genetic message, ii. Effect of initiation factors on the binding of formyl-methionyl-trna to ribosomes.

2. Protein measurement with the Folin phenol reagent.

3. Separation of three microbial amino acid polymerization factors.

4. Translation of the genetic message. VII. Role of initiation factors in formation of the chain initiation complex with Escherichia coli ribosomes.

5. Release factors differing in specificity for terminator codons.

6. Peptide chain termination. 3. Stimulation of in vitro termination.

Review 7. Polypeptide chain elongation in protein biosynthesis.

Review 8. Mechanism of protein biosynthesis.

9. Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomes.

10. Sequential translation of trinucleotide codons for the initiation and termination of protein synthesis.

1. Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex.

2. Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3.

3. The mechanism of tryptophan induction of tryptophanase operon expression: tryptophan inhibits release factor-mediated cleavage of TnaC-peptidyl-tRNA(Pro).

Review 4. The mechanism of peptide chain termination.

5. Peptide chain termination with mammalian release factor.

6. Peptide chain termination. VII. The ribosomal and release factor requirements for peptide release.

7. Peptide chain termination: effect of protein S on ribosomal binding of release factors.

8. Localization and characterization of the gene encoding release factor RF3 in Escherichia coli.

9. Influence of guanine nucleotides and elongation factors on interaction of release factors with the ribosome.

10. Connection between stop codon reassignment and frequent use of shifty stop frameshifting.