Literature DB >> 4900147

Topical ampicillin in the appendicectomy wound: report of double-blind trial.

J W Rickett, B T Jackson.   

Abstract

One hundred and thirty unselected patients undergoing appendicectomy were treated with topical ampicillin powder or topical placebo powder (lactose) before closing the wound. The postoperative wound infection rates were 3% in the ampicillin-treated group and 24% in the control group, a significant difference. This difference was not influenced by the degree of inflammation in the appendix. No side-effects of treatment were observed.

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 4900147      PMCID： PMC1629853          DOI： 10.1136/bmj.4.5677.206

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  19 in total

1.  APPENDICECTOMY WOUND INFECTION, DRAINAGE, AND ANTIBIOTICS.

Authors:  J VINNICOMBE
Journal:  Br J Surg       Date:  1964-05       Impact factor: 6.939

2.  WOUND SEPSIS AFTER CLEAN OPERATIONS.

Authors:  U LJUNGQVIST
Journal:  Lancet       Date:  1964-05-16       Impact factor: 79.321

3.  PROPHYLACTIC TOPICAL USE OF ANTIBIOTICS IN SURGICAL WOUNDS: A CONTROLLED CLINICAL TRIAL USING "POLYBACTRIN".

Authors:  G FIELDING; A RAO; N C DAVIS; N WERNIGK
Journal:  Med J Aust       Date:  1965-07-24       Impact factor: 7.738

4.  A reappraisal of the effects of antimicrobial therapy on the course of appendicitis in children.

Authors:  W R COLE; H R BERNARD
Journal:  Am Surg       Date:  1961-01       Impact factor: 0.688

5.  The prevention of wound injection following contamination with colon organisms.

Authors:  A O SINGLETON; D DAVIS; J JULIAN
Journal:  Surg Gynecol Obstet       Date:  1959-04

6.  Application of antibiotics (polybactrin) in surgical practice, using the aerosol technique.

Authors:  R M GIBSON
Journal:  Br Med J       Date:  1958-06-07

7.  The use of topical antibiotics in the prevention of experimental wound infection.

Authors:  W B Hopson; L Britt; R T Sherman; C P Ledes
Journal:  J Surg Res       Date:  1968-06       Impact factor: 2.192

8.  Prophylactic antimicrobial drugs in surgery.

Authors:  R C Karl; J J Mertz; F J Veith; P Dineen
Journal:  N Engl J Med       Date:  1966-08-11       Impact factor: 91.245

9.  An investigation to evaluate a topical antibiotic in the prevention of wound sepsis in a casualty department.

Authors:  D Caro; K W Reynolds; J De Smith
Journal:  Br J Clin Pract       Date:  1967-12

10.  Wound infection prevention by topical antibiotics.

Authors:  E A Ryan
Journal:  Br J Surg       Date:  1967-05       Impact factor: 6.939
View more
  12 in total

1.  Topical ampicillin against wound infection after colorectal surgery.

Authors:  B Andersen; B Korner; A H Ostergaard
Journal:  Ann Surg       Date:  1972-08       Impact factor: 12.969

2.  [Infected wounds].

Authors:  F W Gierhake
Journal:  Langenbecks Arch Chir       Date:  1982

3.  Wound infections in appendicitis: effective prophylaxis.

Authors:  P R Gaffney
Journal:  World J Surg       Date:  1984-06       Impact factor: 3.352

4.  Antimicrobial prophylaxis in appendectomy patients.

Authors:  F Gottrup; T K Hunt
Journal:  World J Surg       Date:  1982-05       Impact factor: 3.352

5.  Wound infection rates after intraincisional plus systemic antibiotic prophylaxis in an animal model.

Authors:  F Moesgaard; M C Lykkegaard Nielsen; T Justesen
Journal:  Eur J Clin Microbiol       Date:  1984-12       Impact factor: 3.267

6.  The proper use of local antimicrobial agents in wounds.

Authors:  J A Moylan
Journal:  World J Surg       Date:  1980-07       Impact factor: 3.352

7.  Prophylaxis of infection after appendicectomy: a survey of current surgical practice.

Authors:  W B Campbell
Journal:  Br Med J       Date:  1980-12-13

8.  Metronidazole v ampicillin: differing effects on the postoperative recovery.

Authors:  A D Chant; D T Turner; D Machin
Journal:  Ann R Coll Surg Engl       Date:  1984-03       Impact factor: 1.891

9.  Metronidazole in prevention and treatment of bacteroides infections after appendicectomy.

Authors:  A T Willis; I R Ferguson; P H Jones; K D Phillips; P V Tearle; R B Berry; R V Fiddian; D F Graham; D H Harland; D B Innes; W M Mee; R L Rothwell-Jackson; I Sutch; C Kilbey; D Edwards
Journal:  Br Med J       Date:  1976-02-07

10.  Computer-aided prediction of gangrenous and perforating appendicitis.

Authors:  D F Graham
Journal:  Br Med J       Date:  1977-11-26
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.