| Literature DB >> 764935 |
A T Willis, I R Ferguson, P H Jones, K D Phillips, P V Tearle, R B Berry, R V Fiddian, D F Graham, D H Harland, D B Innes, W M Mee, R L Rothwell-Jackson, I Sutch, C Kilbey, D Edwards.
Abstract
The frequency of non-clostridial anaerobic infection was studied in 95 patients who had undergone acute appendicectomy: 49 received prophylactic metronidazole and 46 received placebo. Anaerobic infection did not develop in any of the metronidazole-treated patients, but infections did develop in nine (19%) of the 46 controls. Metronidazole is conveniently administered by suppository to patients who cannot take oral drugs. Five patients with intra-abdominal infections caused by non-clostridial anaerobes were successfully treated with metronidazole.Entities:
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Year: 1976 PMID： 764935 PMCID： PMC1638715 DOI： 10.1136/bmj.1.6005.318
Source DB: PubMed Journal: Br Med J ISSN： 0007-1447