Literature DB >> 4886608

Erythromycin-resistant mutant of Escherichia coli with altered ribosomal protein component.

K Tanaka, H Teraoka, M Tamaki, E Otaka, S Osawa.   

Abstract

Erythromycin combines with 50S ribosomal subunit of an erythromycin-sensitive Escherichia coli (strain Q13), while ribosomes from an erythromycin-resistant mutant from this strain have little affinity for the antibiotic. A protein component of the 50S subunit of the mutant strain is distinct from that of the parent Q13 strain.

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Year:  1968        PMID： 4886608     DOI： 10.1126/science.162.3853.576

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Biogenesis of mitochondria 27. Genetic and biochemical characterisation of cytoplasmic and nuclear mutations to spiramycin resistance in Saccharomyces cerevisiae.

Authors:  M K Trembath; C L Bunn; H B Lukins; A W Linnane
Journal:  Mol Gen Genet       Date:  1973

2.  Phenotypes represented by a mutational change in a 50s ribosomal protein component, 50-8, in Escherichia coli.

Authors:  K Tanaka; H Teraoka; M Tamaki; R Takata; S Osawa
Journal:  Mol Gen Genet       Date:  1972

3.  An altered chloroplast ribosomal protein in ery-M1 mutants of Chlamydomonas reinhardi.

Authors:  J N Davidson; M R Hanson; L Bogorad
Journal:  Mol Gen Genet       Date:  1974

4.  Studies on ribosomal mutants of Salmonella typhimurium LT-2.

Authors:  B Tyler; J L Ingraham
Journal:  Mol Gen Genet       Date:  1973-05-09

5.  Genetic studies of the ribosomal proteins in Escherichia coli. IV. Pattern of the alteration of ribosomal protein components in mutants resistant to spectinomycin or erythromycin in different strains of Escherichia coli.

Authors:  S Dekio; R Takata; S Osawa; K Tanaka; M Tamaki
Journal:  Mol Gen Genet       Date:  1970

6.  Genetic studies of he ribosoml proteis in Escherichaoli. V. Mapp-ing of erythromycin resistance mutations which lea to alteration of a 50s ribosomal protein component.

Authors:  R Takata; S Osawa; K Tanaka; H Teraoka; M Tamaki
Journal:  Mol Gen Genet       Date:  1970

7.  [Selection of actidion-resistant mutants in Neurospora crassa and their genetical and biochemical analysis].

Authors:  A Neuhäuser; W Klingmüller; F Kaudewitz
Journal:  Mol Gen Genet       Date:  1970

8.  Drastic alteration of ribosomal RNA and ribosomal proteins in showdomycin-resistant Escherichia coli.

Authors:  M Beljanski; P Bourgarel; M Beljanski
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205

9.  Analysis of ribosomes from viomycin-sensitive and -resistant strains of Mycobacterium smegmatis.

Authors:  T Yamada; K Masuda; K Shoji; M Hori
Journal:  J Bacteriol       Date:  1972-10       Impact factor: 3.490

10.  Peptide analyses of a protein component, 50-8, of 50s ribosomal subunit from erythromycin resistant mutants of Escherichia coli and Escherichia freudii.

Authors:  E Otaka; T Itoh; S Osawa; K Tanaka; M Tamaki
Journal:  Mol Gen Genet       Date:  1972
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