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Literature DB >> 5277106

Drastic alteration of ribosomal RNA and ribosomal proteins in showdomycin-resistant Escherichia coli.

Abstract

In a mutant of Escherichia coli resistant to showdomycin, both the 50S and 30S ribosomal subunits contain RNA species in which the purine concentration greatly exceeds that of pyrimidines. The same is true for total rapidly-labeled RNA. The modified ribosomal RNA hybridizes poorly with homologous DNA, which is apparently unchanged in base composition. Acrylamide gel electrophoresis of mutant ribosomal proteins shows a highly altered protein pattern for both ribosomal subunits, although the activity of these ribosomes is not decreased.

Entities: Chemical Species

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Year: 1971 PMID： 5277106 PMCID： PMC388967 DOI： 10.1073/pnas.68.2.491

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

21 in total

1. THE CHROMOSOMAL SITE SPECIFYING A RIBOSOMAL PROTEIN IN ESCHERICHIA COLI.

Authors: P S LEBOY; E C COX; J G FLAKS
Journal: Proc Natl Acad Sci U S A Date: 1964-12 Impact factor: 11.205

2. Studies on the composition of the protein from Escherichia coli ribosomes.

Authors: J P WALLER; J I HARRIS
Journal: Proc Natl Acad Sci U S A Date: 1961-01-15 Impact factor: 11.205

3. Aspects of the stability of a bacterial ribonucleic acid.

Authors: J HOROWITZ; A LOMBARD; E CHARGAFF
Journal: J Biol Chem Date: 1958-12 Impact factor: 5.157

4. PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS.

Authors: M Nomura; C V Lowry
Journal: Proc Natl Acad Sci U S A Date: 1967-09 Impact factor: 11.205

5. The chemical and genetic structure of bacterial ribosomes.

Authors: P S Sypherd; D M O'Neil; M M Taylor
Journal: Cold Spring Harb Symp Quant Biol Date: 1969

6. On the catalytic center of peptidyl transfer: a part of the 50 S ribosome structure.

Authors: T Staehelin; D M Maglott; R E Monro
Journal: Cold Spring Harb Symp Quant Biol Date: 1969

7. [Showdomycin and biosynthesis of RNA non complementary to DNA. I].

Authors: M Beljanski; P Bourgarel; M Beljanski
Journal: Ann Inst Pasteur (Paris) Date: 1970-03

8. Changes in ribosomal proteins associated with mutants in a locus that affects Escherichia coli ribosomes.

Authors: J Krembel; D Apirion
Journal: J Mol Biol Date: 1968-04-28 Impact factor: 5.469

9. Three genes that affect Escherichia coli ribosomes.

Authors: D Apirion
Journal: J Mol Biol Date: 1967-12-14 Impact factor: 5.469

10. Structure and function of E. coli ribosomes. V. Reconstitution of functionally active 30S ribosomal particles from RNA and proteins.

Authors: P Traub; M Nomura
Journal: Proc Natl Acad Sci U S A Date: 1968-03 Impact factor: 11.205

5 in total

Drastic alteration of ribosomal RNA and ribosomal proteins in showdomycin-resistant Escherichia coli.

1. THE CHROMOSOMAL SITE SPECIFYING A RIBOSOMAL PROTEIN IN ESCHERICHIA COLI.

2. Studies on the composition of the protein from Escherichia coli ribosomes.

3. Aspects of the stability of a bacterial ribonucleic acid.

4. PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS.

5. The chemical and genetic structure of bacterial ribosomes.

6. On the catalytic center of peptidyl transfer: a part of the 50 S ribosome structure.

7. [Showdomycin and biosynthesis of RNA non complementary to DNA. I].

8. Changes in ribosomal proteins associated with mutants in a locus that affects Escherichia coli ribosomes.

9. Three genes that affect Escherichia coli ribosomes.

10. Structure and function of E. coli ribosomes. V. Reconstitution of functionally active 30S ribosomal particles from RNA and proteins.

1. RNA-bound reverse transcriptase in Escherichia coli and in vitro synthesis of a complementary DNA.

2. Analysis of ribosomes from viomycin-sensitive and -resistant strains of Mycobacterium smegmatis.

3. Particular small size RNA and RNA fragments from different origins as tumor inducing agents in Datura stramonium.

4. Transformation of Agrobacterium tumefaciens into a non-oncogenic species by an Escherichia coli RNA.

5. Isolation of the tumor-inducing RNA from oncogenic and nononcogenic Agrobacterium tumefaciens.