Literature DB >> 488283

Dissociation constants of 4-acetoxy-piperidines and -thiacyclohexanes at the muscarinic receptor.

G Lambrecht.   

Abstract

The dissociation constants (KA) and the relative intrinsic efficacies (e) of 4-acetoxy-piperidines and -thiacyclohexanes were determined on the guinea-pig isolated left atrium. The differences in the muscarinic potencies are associated with differences in affinities and efficacies, respectively.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 488283     DOI： 10.1007/bf01963296

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  A modification of receptor theory.

Authors:  R P STEPHENSON
Journal:  Br J Pharmacol Chemother       Date:  1956-12

Review 2.  Biochemical studies on muscarinic acetylcholine receptors.

Authors:  N J Birdsall; E C Hulme
Journal:  J Neurochem       Date:  1976-07       Impact factor: 5.372

3.  [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogs. 5. The stereochemistry of cis- and trans-4-acetoxy-1-methylthioniacyclohexanes].

Authors:  G Lambrecht
Journal:  Arch Pharm (Weinheim)       Date:  1978-07       Impact factor: 3.751

4.  Structure-activity relationships of cyclic acetylcholine analogues of the piperidinol and thiacyclohexanol series.

Authors:  G Lambrecht
Journal:  Experientia       Date:  1976-03-15

5.  The rate of action of cyclic ammonium and sulfonium analogues of acetylcholine.

Authors:  G Lambrecht
Journal:  Experientia       Date:  1979-01-15
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.