Literature DB >> 4808857

Ethane evolution: a new index of lipid peroxidation.

C A Riely, G Cohen, M Lieberman.   

Abstract

Homogenates of mouse liver and brain at 37 degrees C spontaneously formed lipid peroxides and simultaneously evolved ethane. alpha-Tocopherol, a lipid antioxidant, blocked ethane formation. When mice were injected with carbon tetrachloride (a liquid prooxidant for liver), the animals produced ethane. Ethane evolution in vivo was stimulated by prior administration of phenobarbital and it was diminished by prior injection of alpha-tocopherol. These data suggest that ethane production may be a useful index of lipid peroxidation in tissue homogenates and in intact animals.

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Year:  1974        PMID: 4808857     DOI: 10.1126/science.183.4121.208

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  68 in total

1.  Maintenance of plant cell membrane integrity and function by the immobilisation of protoplasts in alginate matrices.

Authors:  H Schnabl; R J Youngman; U Zimmermann
Journal:  Planta       Date:  1983-08       Impact factor: 4.116

2.  NMDA receptor antagonists prevent acute ammonia toxicity in mice.

Authors:  C Hermenegildo; G Marcaida; C Montoliu; S Grisolía; M D Miñana; V Felipo
Journal:  Neurochem Res       Date:  1996-10       Impact factor: 3.996

3.  Lipid peroxidation in isolated hepatocytes from rats ingesting ethanol chronically.

Authors:  H Remmer; D Albrecht; H Kappus
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-06       Impact factor: 3.000

Review 4.  Free radicals and oxygen toxicity.

Authors:  D D Buechter
Journal:  Pharm Res       Date:  1988-05       Impact factor: 4.200

5.  Absence of lipid peroxidation as determined by ethane exhalation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD).

Authors:  L W Robertson; U Regel; J G Filser; F Oesch
Journal:  Arch Toxicol       Date:  1985-04       Impact factor: 5.153

6.  Volatile alkanes produced by erythrocytes: an assay for in vitro studies on lipid peroxidation.

Authors:  M R Clemens; H Remmer
Journal:  Blut       Date:  1982-11

7.  Volatile hydrocarbon and carbonyl products of lipid peroxidation: a comparison of pentane, ethane, hexanal, and acetone as in vivo indices.

Authors:  C J Dillard; A L Tappel
Journal:  Lipids       Date:  1979-12       Impact factor: 1.880

8.  Inhibition of paraquat phytotoxicity by a novel copper chelate with superoxide dismutating activity.

Authors:  R J Youngman; A D Dodge; E Lengfelder; E F Elstner
Journal:  Experientia       Date:  1979-10-15

9.  Mechanisms of lipid peroxidation: iron catalyzed decomposition of fatty acid hydroperoxides as the basis of hydrocarbon evolution in vivo.

Authors:  D H Donovan; D B Menzel
Journal:  Experientia       Date:  1978-06-15

10.  Long-term effects of commercial and congeneric polychlorinated biphenyls on ethane production and malondialdehyde levels, indicators of in vivo lipid peroxidation.

Authors:  S Dogra; J G Filser; C Cojocel; H Greim; U Regel; F Oesch; L W Robertson
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

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