Literature DB >> 4774404

The potentiation of growth hormone by asparagine and tryptophan.

J H Ottaway.   

Abstract

Asparagine potentiates the growth-promoting effect of bovine growth hormone in rats when injected 3h after the latter, but not earlier. Tryptophan potentiates only when injected simultaneously with the hormone. The possible mode of action of growth hormone, and the likelihood that asparagine is a limiting factor in the growth of animals, are discussed.

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Year:  1973        PMID： 4774404      PMCID： PMC1165973          DOI： 10.1042/bj1360441

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  The effect of insulin on amino acid metabolism.

Authors:  T HERNANDEZ; R A COULSON
Journal:  Biochem J       Date:  1961-06       Impact factor: 3.857

2.  Tryptophan deficiency.

Authors:  R S Alcock
Journal:  Biochem J       Date:  1934       Impact factor: 3.857

Review 3.  Human growth hormone.

Authors:  J M Tanner
Journal:  Nature       Date:  1972-06-23       Impact factor: 49.962

4.  Concentrations of asparagine in tissues of prepubertal rats after enzymic or dietary depletion of asparagine.

Authors:  D L Frankel; H Wells; L C Fillios
Journal:  Biochem J       Date:  1973-03       Impact factor: 3.857

5.  Amino acid diets and maximal growth in the rat.

Authors:  Q R Rogers; A E Harper
Journal:  J Nutr       Date:  1965-11       Impact factor: 4.798

Review 6.  Protein synthesis and breakdown and amino acid catabolism in protein-calorie malnutrition.

Authors:  W P James
Journal:  Proc Nutr Soc       Date:  1972-09       Impact factor: 6.297

Review 7.  Dietary effects on the secretion and actions of growth hormone.

Authors:  M R Turner
Journal:  Proc Nutr Soc       Date:  1972-09       Impact factor: 6.297

8.  Stimulation of insulin secretion by amino acids.

Authors:  J C Floyd; S S Fajans; J W Conn; R F Knopf; J Rull
Journal:  J Clin Invest       Date:  1966-09       Impact factor: 14.808

9.  Influence of amino acid supply on ribosomes and protein synthesis of perfused rat liver.

Authors:  L S Jefferson; A Korner
Journal:  Biochem J       Date:  1969-03       Impact factor: 3.857

10.  Brain serotonin content: physiological dependence on plasma tryptophan levels.

Authors:  J D Fernstrom; R J Wurtman
Journal:  Science       Date:  1971-07-09       Impact factor: 47.728
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