Literature DB >> 477235

A defect in zinc uptake by jejunal biopsies in acrodermatitis enteropathica.

D J Atherton, D P Muller, P J Aggett, J T Harries.   

Abstract

1. In a system in vitro, 65Zn accumulation by jejunal mucosal biopsies from patients with acrodermatitis enteropathica was found to be markedly reduced compared with controls. 2. We suggest that defective uptake of zinc by enterocytes is the primary abnormality responsible for the zinc deficiency underlying this disorder.

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Year:  1979        PMID： 477235     DOI： 10.1042/cs0560505

Source DB:  PubMed          Journal:  Clin Sci (Lond)        ISSN： 0143-5221            Impact factor:   6.124


  18 in total

Review 1.  Current status of zinc in health and disease states.

Authors:  P J Aggett; J T Harries
Journal:  Arch Dis Child       Date:  1979-12       Impact factor: 3.791

2.  The role of the pancreas in the regulation of zinc status.

Authors:  J P Van Wouwe; J J Uijlenbroek
Journal:  Biol Trace Elem Res       Date:  1994-08       Impact factor: 3.738

Review 3.  Maintenance of Intestinal Epithelial Homeostasis by Zinc Transporters.

Authors:  Wakana Ohashi; Takafumi Hara; Teruhisa Takagishi; Koji Hase; Toshiyuki Fukada
Journal:  Dig Dis Sci       Date:  2019-03-04       Impact factor: 3.199

Review 4.  Paediatric gastroenterology: lessons of inborn errors.

Authors:  P J Milla
Journal:  Postgrad Med J       Date:  1986-02       Impact factor: 2.401

5.  The effect of the acrodermatitis enteropathica mutation on zinc uptake in human fibroblasts.

Authors:  F Vazquez; A Grider
Journal:  Biol Trace Elem Res       Date:  1995-11       Impact factor: 3.738

6.  Acrodermatitis enteropathica.

Authors:  P J Aggett
Journal:  J Inherit Metab Dis       Date:  1983       Impact factor: 4.982

7.  Zinc deficiency and its inherited disorders -a review.

Authors:  M Leigh Ackland; Agnes Michalczyk
Journal:  Genes Nutr       Date:  2006-03       Impact factor: 5.523

8.  Symptomatic zinc deficiency in a breast-fed preterm infant.

Authors:  P J Aggett; D J Atherton; J More; J Davey; H T Delves; J T Harries
Journal:  Arch Dis Child       Date:  1980-07       Impact factor: 3.791

9.  The therapeutic effect of amphotericin in acrodermatitis enteropathica: hypothesis and implications.

Authors:  P J Aggett; H T Delves; J M Thorn; D J Atherton; J T Harris; A D Bangham
Journal:  Eur J Pediatr       Date:  1981-09       Impact factor: 3.183

10.  Analysis of zinc transporter, hZnT4 ( Slc30A4), gene expression in a mammary gland disorder leading to reduced zinc secretion into milk.

Authors:  Agnes Michalczyk; George Varigos; Anthony Catto-Smith; Rachael C Blomeley; M Leigh Ackland
Journal:  Hum Genet       Date:  2003-05-13       Impact factor: 4.132
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