Literature DB >> 4732523

Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats.

H Yoshimura, S Ida, K Oguri, H Tsukamoto.   

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Year:  1973        PMID: 4732523     DOI: 10.1016/0006-2952(73)90320-1

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  23 in total

1.  Morphine-6 beta-glucuronide has a higher efficacy than morphine as a mu-opioid receptor agonist in the rat locus coeruleus.

Authors:  P B Osborne; B Chieng; M J Christie
Journal:  Br J Pharmacol       Date:  2000-12       Impact factor: 8.739

2.  Analgesic and immunomodulatory effects of codeine and codeine 6-glucuronide.

Authors:  V Srinivasan; D Wielbo; J Simpkins; J Karlix; K Sloan; I Tebbett
Journal:  Pharm Res       Date:  1996-02       Impact factor: 4.200

Review 3.  Enterohepatic circulation of opioid drugs. Is it clinically relevant in the treatment of cancer patients?

Authors:  G W Hanks; P J Wand
Journal:  Clin Pharmacokinet       Date:  1989-08       Impact factor: 6.447

4.  Effects of morphine metabolites on micturition in normal, unanaesthetized rats.

Authors:  Y Igawa; D Westerling; A Mattiasson; K E Andersson
Journal:  Br J Pharmacol       Date:  1993-09       Impact factor: 8.739

5.  Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: a microdialysis study.

Authors:  M J Barjavel; J M Scherrmann; H N Bhargava
Journal:  Br J Pharmacol       Date:  1995-12       Impact factor: 8.739

6.  Elevated concentrations of morphine 6-beta-D-glucuronide in brain extracellular fluid despite low blood-brain barrier permeability.

Authors:  F Stain-Texier; G Boschi; P Sandouk; J M Scherrmann
Journal:  Br J Pharmacol       Date:  1999-10       Impact factor: 8.739

7.  The pharmacokinetics of morphine and morphine glucuronide metabolites after subcutaneous bolus injection and subcutaneous infusion of morphine.

Authors:  R Stuart-Harris; S P Joel; P McDonald; D Currow; M L Slevin
Journal:  Br J Clin Pharmacol       Date:  2000-03       Impact factor: 4.335

8.  Pharmacokinetics of nicomorphine and its metabolites in man after epidural administration.

Authors:  P M Koopman-Kimenai; T B Vree; M A Hasenbos; E W Weber; C P Verweij-Van Wissen; L H Booij
Journal:  Pharm Weekbl Sci       Date:  1991-06-21

Review 9.  High-dose morphine and methadone in cancer patients. Clinical pharmacokinetic considerations of oral treatment.

Authors:  J Säwe
Journal:  Clin Pharmacokinet       Date:  1986 Mar-Apr       Impact factor: 6.447

Review 10.  Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors.

Authors:  H K Kroemer; U Klotz
Journal:  Clin Pharmacokinet       Date:  1992-10       Impact factor: 6.447

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