Literature DB >> 2570655

Enterohepatic circulation of opioid drugs. Is it clinically relevant in the treatment of cancer patients?

G W Hanks1, P J Wand.   

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Year:  1989        PMID: 2570655     DOI: 10.2165/00003088-198917020-00001

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN: 0312-5963            Impact factor:   6.447


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  28 in total

1.  Distribution and fate of morphine in non-tolerant and tolerant dogs and rats.

Authors:  L A WOODS
Journal:  J Pharmacol Exp Ther       Date:  1954-10       Impact factor: 4.030

2.  Morphine-6-glucuronide has high affinity for the opioid receptor.

Authors:  C B Christensen; L N Jørgensen
Journal:  Pharmacol Toxicol       Date:  1987-01

3.  Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats.

Authors:  H Yoshimura; S Ida; K Oguri; H Tsukamoto
Journal:  Biochem Pharmacol       Date:  1973-06-15       Impact factor: 5.858

4.  Analgesic effect of morphine glucuronides.

Authors:  K Shimomura; O Kamata; S Ueki; S Ida; K Oguri; H Yoshimura; H Tsukamoto
Journal:  Tohoku J Exp Med       Date:  1971-09       Impact factor: 1.848

5.  Oral morphine in cancer patients: in vivo kinetics and in vitro hepatic glucuronidation.

Authors:  J Säwe; L Kager; J O Svensson Eng; A Rane
Journal:  Br J Clin Pharmacol       Date:  1985-04       Impact factor: 4.335

6.  Drugs for pain.

Authors:  L Lasagna
Journal:  Br Med J       Date:  1979-08-04

7.  Pharmacokinetic interpretation of the enterohepatic recirculation and first-pass elimination of morphine in the rat.

Authors:  B E Dahlström; L K Paalzow
Journal:  J Pharmacokinet Biopharm       Date:  1978-12

Review 8.  High-dose morphine and methadone in cancer patients. Clinical pharmacokinetic considerations of oral treatment.

Authors:  J Säwe
Journal:  Clin Pharmacokinet       Date:  1986 Mar-Apr       Impact factor: 6.447

9.  Studies of the enterohepatic circulation of morphine in the rat.

Authors:  C T Walsh; R R Levine
Journal:  J Pharmacol Exp Ther       Date:  1975-11       Impact factor: 4.030

10.  Relative bioavailability of controlled release morphine tablets (MST continus) in cancer patients.

Authors:  P Poulain; P J Hoskin; G W Hanks; O A-Omar; V A Walker; A Johnston; P Turner; G W Aherne
Journal:  Br J Anaesth       Date:  1988-11       Impact factor: 9.166

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  3 in total

Review 1.  Multiple peaking phenomena in pharmacokinetic disposition.

Authors:  Neal M Davies; Jody K Takemoto; Dion R Brocks; Jaime A Yáñez
Journal:  Clin Pharmacokinet       Date:  2010-06       Impact factor: 6.447

2.  Morphine pharmacokinetics and metabolism in humans. Enterohepatic cycling and relative contribution of metabolites to active opioid concentrations.

Authors:  J Hasselström; J Säwe
Journal:  Clin Pharmacokinet       Date:  1993-04       Impact factor: 6.447

3.  Rectal administration of nicomorphine in patients improves biological availability of morphine and its glucuronide conjugates.

Authors:  P M Koopman-Kimenai; T B Vree; L H Booij; R Dirksen
Journal:  Pharm World Sci       Date:  1994-12-02
  3 in total

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