| Literature DB >> 4610577 |
J D Friesen, N P Fiil, J M Parker, W A Haseltine.
Abstract
A new relaxed mutant called rel C has been isolated from a rel A(+)/rel A(+) partial diploid strain. The rel C mutant is unable to synthesize ppGpp or pppGpp in vivo in response to amino acid starvation or in vitro, but can synthesize these nucleotides in a shift-down. Rel C maps near rif. Studies in vitro demonstrate the lesion to be probably in one of the 50S ribosomal proteins that can be removed by 1.0 M LiCl.Entities:
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Year: 1974 PMID： 4610577 PMCID： PMC433794 DOI： 10.1073/pnas.71.9.3465
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205