Literature DB >> 4586777

Studies on the biosynthesis of alpha-putrescinylthymine in bacteriophage phi W-14-infected Pseudomonas acidovorans.

R A Kelln, R A Warren.   

Abstract

The alpha-putrescinylthymine (putThy) in bacteriophage phiW-14 DNA is synthesized at the mononucleotide level: it is labeled by uracil or deoxyuridine but not by thymidine, and it appears in the acid-soluble pool of infected cells before the onset of phage DNA synthesis. The methylene group at the C-5 position of the pyrimidine moiety of putThy is derived in vivo from a C(1) unit. Extracts of a phage infected thymidine auxotroph of the host, Pseudomonas acidovorans, apparently contain a phage-specific thymidylate synthetase and a phage-specific activity which forms 5-hydroxymethyl dUMP from N(5), N(10)-methylene-tetrahydrofolate and dUMP.

Entities:  

Mesh：

Substances：

Year:  1973        PMID： 4586777      PMCID： PMC356784     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Properties of thymidylate synthetase from dichloromethotrexate-resistant Lactobacillus casei.

Authors:  T C Crusberg; R Leary; R L Kisliuk
Journal:  J Biol Chem       Date:  1970-10-25       Impact factor: 5.157

Review 2.  Pyrimidine metabolism in microorganisms.

Authors:  G A O'Donovan; J Neuhard
Journal:  Bacteriol Rev       Date:  1970-09

3.  The biosynthesis of 5-hydroxymethyldeoxyuridylic acid in bacteriophage-infected Bacillus subtilis.

Authors:  D H Roscoe; R G Tucker
Journal:  Virology       Date:  1966-05       Impact factor: 3.616

4.  Isolation and properties of a Pseudomonas acidovorans bacteriophage.

Authors:  A M Kropinski; R A Warren
Journal:  J Gen Virol       Date:  1970-01       Impact factor: 3.891

5.  A new assay of thymidylate synthetase activity based on the release of tritium from deoxyuridylate-5-3-H.

Authors:  M I Lomax; G R Greenberg
Journal:  J Biol Chem       Date:  1967-01-10       Impact factor: 5.157

6.  Early intracellular events in the replication of T4 phage DNA. I. Complex formation of replicative DNA.

Authors:  A W Kozinski; T H Lin
Journal:  Proc Natl Acad Sci U S A       Date:  1965-07       Impact factor: 11.205

7.  Control of DNA synthesis in Bacillus subtilis by phage phi e.

Authors:  M Marcus; M C Newlon
Journal:  Virology       Date:  1971-04       Impact factor: 3.616

8.  The aerobic pseudomonads: a taxonomic study.

Authors:  R Y Stanier; N J Palleroni; M Doudoroff
Journal:  J Gen Microbiol       Date:  1966-05

9.  Biological effects of substituting cytosine for 5-hydroxymethylcytosine in the deoxyribonucleic acid of bacteriophage T4.

Authors:  E M Kutter; J S Wiberg
Journal:  J Virol       Date:  1969-10       Impact factor: 5.103

10.  Deoxycytidine triphosphate deaminase: characterization of an Escherichia coli mutant deficient in the enzyme.

Authors:  G A O'Donovan; G Edlin; J A Fuchs; J Neuhard; E Thomassen
Journal:  J Bacteriol       Date:  1971-02       Impact factor: 3.490
View more
  10 in total

1.  Alkali lability of bacteriophage phi W-14 DNA.

Authors:  H A Lewis; R C Miller; J C Stone; R A Warren
Journal:  J Virol       Date:  1975-12       Impact factor: 5.103

2.  Polypeptide synthesis directed by bacteriophage phi W-14 and by mutants defective in DNA synthesis.

Authors:  P B Miller; B Gerhard; R A Warren
Journal:  J Virol       Date:  1984-05       Impact factor: 5.103

3.  Uptake and fate of bacteriophage phi W-14 DNA in competent Bacillus subtilis.

Authors:  P Lopez; M Espinosa; M Piechowska; D Shugar; R A Warren
Journal:  J Bacteriol       Date:  1982-02       Impact factor: 3.490

4.  Synthesis of thymine and alpha-putrescinylthymine in bacteriophage phi W-14-infected Pseudomonas acidovorans.

Authors:  K L Maltman; J Neuhard; H A Lewis; R A Warren
Journal:  J Virol       Date:  1980-05       Impact factor: 5.103

5.  Deoxythymidine nucleotide metabolism in Bacillus subtilis W23 infected with bacteriophage SP1Oc: preliminary evidence that dTMP in SP10c DNA is synthesized by a novel, bacteriophage-specific mechanism.

Authors:  O Markewych; E Casella; M Dosmar; H Witmer
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

6.  Bacteriophage phi W-14-infected Pseudomonas acidovorans synthesizes hydroxymethyldeoxyuridine triphosphate.

Authors:  J Neuhard; K L Maltman; R A Warren
Journal:  J Virol       Date:  1980-05       Impact factor: 5.103

7.  Biosynthesis of 5-(4'5'-dihydroxypentyl) uracil as a nucleoside triphosphate in bacteriophage SP15-infected Bacillus subtilis.

Authors:  M S Walker; M Mandel
Journal:  J Virol       Date:  1978-02       Impact factor: 5.103

8.  Isolation and preliminary characterization of amber mutants of bacteriophage phi W-14 defective in DNA synthesis.

Authors:  P B Miller; K L Maltman; R A Warren
Journal:  J Virol       Date:  1982-07       Impact factor: 5.103

9.  Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA.

Authors:  Lakshminarayan M Iyer; Dapeng Zhang; A Maxwell Burroughs; L Aravind
Journal:  Nucleic Acids Res       Date:  2013-06-28       Impact factor: 16.971

10.  The Sequence of Two Bacteriophages with Hypermodified Bases Reveals Novel Phage-Host Interactions.

Authors:  Andrew M Kropinski; Dann Turner; John H E Nash; Hans-Wolfgang Ackermann; Erika J Lingohr; Richard A Warren; Kenneth C Ehrlich; Melanie Ehrlich
Journal:  Viruses       Date:  2018-04-24       Impact factor: 5.048
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.