| Literature DB >> 4749757 |
J K Dawborn, M D Page, D J Schiavone.
Abstract
The plasma level and elimination of 5-fluorocytosine (5-FC) was measured in normal subjects and patients with impaired renal function. Prolongation of the half-life of the drug in renal failure has been confirmed. Renal clearance of 5-FC was about 75% of the creatinine clearance and a corresponding modification of drug dosage should be made in patients with renal insufficiency.Entities:
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Year: 1973 PMID： 4749757 PMCID： PMC1587832 DOI： 10.1136/bmj.4.5889.382
Source DB: PubMed Journal: Br Med J ISSN： 0007-1447