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Literature DB >> 457781

Temporal organization of replication in DNA fibers of mammalian cells.

Abstract

The extent of coordinate control over the multiple initiation events in DNA replication has been investigated in three mammalian cell lines by DNA fiber autoradiography. Quantitative estimates have been obtained of the degree of synchrony among initiations occurring on stretches of DNA. Synchrony decreases markedly with increasing distance between initiation sites in MDBK (bovine) and L929 (mouse) cells, but only slightly in muntjac cells. Possible control mechanisms for the initiation process are discussed.

Entities: Disease Species

Mesh：

Year: 1979 PMID： 457781 PMCID： PMC2110389 DOI： 10.1083/jcb.81.3.692

Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539

24 in total

1. Amino acid metabolism in mammalian cell cultures.

Authors: H EAGLE
Journal: Science Date: 1959-08-21 Impact factor: 47.728

2. STUDIES ON THE MECHANISM OF POLIOVIRUS-INDUCED CELL DAMAGE. I. THE RELATION BETWEEN POLIOVIRUS,-INDUCED METABOLIC AND MORPHOLOGICAL ALTERATIONS IN CULTURED CELLS.

Authors: R BABLANIAN; H J EGGERS; I TAMM
Journal: Virology Date: 1965-05 Impact factor: 3.616

3. Molecular events in the reproduction of animal cells. II. The focalized synthesis of DNA in the chromosomes of HeLa cells.

Authors: E STUBBLEFIELD; G C MUELLER
Journal: Cancer Res Date: 1962-10 Impact factor: 12.701

4. The mode of chromosome duplication in Crepis capillaris.

Authors: J H TAYLOR
Journal: Exp Cell Res Date: 1958-10 Impact factor: 3.905

5. Specific nucleotide sequences in HeLa cell inverted repeated DNA: enrichment for sequences found in double-stranded regions of heterogeneous nuclear RNA.

Authors: W R Jelinek
Journal: J Mol Biol Date: 1977-10-05 Impact factor: 5.469

Temporal organization of replication in DNA fibers of mammalian cells.

1. Amino acid metabolism in mammalian cell cultures.

2. STUDIES ON THE MECHANISM OF POLIOVIRUS-INDUCED CELL DAMAGE. I. THE RELATION BETWEEN POLIOVIRUS,-INDUCED METABOLIC AND MORPHOLOGICAL ALTERATIONS IN CULTURED CELLS.

3. Molecular events in the reproduction of animal cells. II. The focalized synthesis of DNA in the chromosomes of HeLa cells.

4. The mode of chromosome duplication in Crepis capillaris.

5. Specific nucleotide sequences in HeLa cell inverted repeated DNA: enrichment for sequences found in double-stranded regions of heterogeneous nuclear RNA.

6. Oligonucleotides in heterogeneous nuclear RNA: similarity of inverted repeats and RNA from repetitious DNA sites.

7. Nucleotide sequence of the origin of replication of the Escherichia coli K-12 chromosome.

8. Nucleotide sequence of Escherichia coli K-12 replication origin.

9. Mapping of inverted repeated DNA sequences within the genome of simian virus 40.

10. MAMMALIAN CHROMOSOMES IN VITRO. 18. DNA REPLICATION IN THE CHINESE HAMSTER.

1. Effect of simian virus 40 on the temporal and spatial organization of DNA replication in Muntjac cells.

2. Effects of reovirus infection on the spatial and temporal organization of DNA replication in L cells.

3. Inhibition of DNA chain elongation in a purine-auxotrophic mutant of Chinese hamster.

4. Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae.