Literature DB >> 4550511

Synthesis of Epstein-Barr virus after activation of the viral genome in a "virus-negative" human lymphoblastoid cell (Raji) made resistant to 5-bromodeoxyuridine (thymidine kinase-virus antigen-immunofluorescence-herpesvirus fingerprints).

B Hampar, J G Derge, L M Martos, J L Walker.   

Abstract

The Raji line of human lymphoblastoid cells, which does not show expression of Epstein-Barr virus, was made resistant to 5-bromodeoxyuridine. Within several weeks after removal of the drug, Epstein-Barr virus particles were detected in the cells. The sequence of virus appearance in the 5-bromodeoxyuridine-resistant cells indicated drug-induced activation of a repressed Epstein-Barr virus genome.

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Year:  1972        PMID： 4550511      PMCID： PMC427548          DOI： 10.1073/pnas.69.1.78

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  The feedback inhibition of thymidine kinase.

Authors:  T R BREITMAN
Journal:  Biochim Biophys Acta       Date:  1963-01-08

2.  DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE.

Authors:  S KIT; D R DUBBS; L J PIEKARSKI; T C HSU
Journal:  Exp Cell Res       Date:  1963-08       Impact factor: 3.905

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Activation of Epstein-Barr virus by 5-bromodeoxyuridine in "virus-free" human cells (complement-fixing antigen-immunofluorescence-leukocytes).

Authors:  P Gerber
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

5.  Presence of EB virus nucleic acid homology in a "virus-free" line of Burkitt tumour cells.

Authors:  H Zur Hausen; H Schulte-Holthausen
Journal:  Nature       Date:  1970-07-18       Impact factor: 49.962

6.  Immunoferritin and immunofluorescent studies with Epstein-Barr virus and herpes simplex virus by use of human sera and hyperimmune rabbit sera.

Authors:  B Hampar; P Gerber; K C Hsu; L M Martos; J L Walker; R F Sigüenza; G A Wells
Journal:  J Natl Cancer Inst       Date:  1970-07       Impact factor: 13.506

7.  Replication of herpes-type virus in a Burkitt lymphoma cell line.

Authors:  Y Hinuma; M Konn; J Yamaguchi; J T Grace
Journal:  J Virol       Date:  1967-12       Impact factor: 5.103

8.  Identification of the filtrable leukocyte-transforming factor of QIMR-WIL cells as herpes-like virus.

Authors:  J H Pope; M K Horne; W Scott
Journal:  Int J Cancer       Date:  1969-05-15       Impact factor: 7.396

9.  Immunofluorescence and herpes-type virus particles in the P3HR-1 Burkitt lymphoma cell line.

Authors:  Y Hinuma; M Konn; J Yamaguchi; D J Wudarski; J R Blakeslee; J T Grace
Journal:  J Virol       Date:  1967-10       Impact factor: 5.103

10.  Transformation and chromosome changes induced by Epstein-Barr virus in normal human leukocyte cultures.

Authors:  P Gerper; J Whang-Peng; J H Monroe
Journal:  Proc Natl Acad Sci U S A       Date:  1969-07       Impact factor: 11.205
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  53 in total

1.  Identification of an intracellular precursor to DNA excreted by human lymphocytes.

Authors:  J C Rogers
Journal:  Proc Natl Acad Sci U S A       Date:  1976-09       Impact factor: 11.205

2.  Growth of B95-8 cells and expression of Epstein-Barr virus lytic phase in serum-free medium.

Authors:  J E Shaw; R G Petit; K Leung
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

3.  Surface marker characteristics and Epstein-Barr virus studies of two established North American Burkitt's lymphoma cell lines.

Authors:  A L Epstein; W Henle; G Henle; J F Hewetson; H S Kaplan
Journal:  Proc Natl Acad Sci U S A       Date:  1976-01       Impact factor: 11.205

4.  Epstein-Barr virus-specific RNA. I. Analysis of viral RNA in cellular extracts and in the polyribosomal fraction of permissive and nonpermissive lymphoblastoid cell lines.

Authors:  S D Hayward; E D Kieff
Journal:  J Virol       Date:  1976-05       Impact factor: 5.103

5.  Activation by 5-iododeoxyuridine of shope papilloma viral genome in cultured VX2 and VX7 carcinomas.

Authors:  T Inokuchi; S Ikejiri; F Mizuno; T Osato
Journal:  Arch Virol       Date:  1975       Impact factor: 2.574

6.  Rescue of Epstein-Barr virus from somatic cell hybrids of Burkitt lymphoblastoid cells.

Authors:  R Glaser; F Rapp
Journal:  J Virol       Date:  1972-08       Impact factor: 5.103

7.  Effects of 5-bromodeoxyuridine and 5-iododeoxyuridine on a latent herpes simplex virus infection.

Authors:  J Varani; J J Kelleher
Journal:  Antimicrob Agents Chemother       Date:  1975-07       Impact factor: 5.191

8.  Viral studies on human brain culture retrieved from cold storage.

Authors:  E T Lennette
Journal:  J Clin Microbiol       Date:  1975-05       Impact factor: 5.948

9.  Rheumatoid factors induce signaling from B cells, leading to Epstein-Barr virus and B-cell activation.

Authors:  Lixin Yang; Masayuki Hakoda; Kazuya Iwabuchi; Tsuyoshi Takeda; Takao Koike; Naoyuki Kamatani; Kenzo Takada
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

10.  Spontaneous cytotoxicity of rheumatoid and normal peripheral blood mononuclear cells against 4 human lymphoblastoid cell lines.

Authors:  J Highton; G S Panayi
Journal:  Ann Rheum Dis       Date:  1980-12       Impact factor: 19.103
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