Literature DB >> 4550512

Activation of Epstein-Barr virus by 5-bromodeoxyuridine in "virus-free" human cells (complement-fixing antigen-immunofluorescence-leukocytes).

P Gerber.   

Abstract

Treatment of three human lymphoid cell lines, free of detectable Epstein-Barr virus, with 5-bromodeoxyuridine resulted in activation of virus synthesis in up to 8% of the cells. The induction of infectious virus could be demonstrated by cocultivation experiments with peripheral leukocytes. These studies demonstrated that the entire viral genome may persist in at least a portion of the lymphoid cells.

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Year:  1972        PMID: 4550512      PMCID: PMC427549          DOI: 10.1073/pnas.69.1.83

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  10 in total

1.  Antibodies in human sera to soluble and viral antigens found in Burkitt lymphoma and other lymphoblastoid cell lines.

Authors:  V Vonka; M Benyesh-Melnick; R M McCombs
Journal:  J Natl Cancer Inst       Date:  1970-04       Impact factor: 13.506

2.  A STUDY OF MALIGNANT TUMOURS IN NIGERIA BY SHORT-TERM TISSUE CULTURE.

Authors:  J V PULVERTAFT
Journal:  J Clin Pathol       Date:  1965-05       Impact factor: 3.411

3.  Persistence of a repressed Epstein-Barr virus genome in Burkitt lymphoma cells made resistant to 5-bromodeoxyuridine.

Authors:  B Hampar; J G Derge; L M Martos; J L Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1971-12       Impact factor: 11.205

4.  Detection of Epstein-Barr viral genome in nonproductive cells.

Authors:  M Nonoyama; J S Pagano
Journal:  Nat New Biol       Date:  1971-09-22

5.  Significance of a complement-fixing antigen associated with herpes-like virus and detected in the Raji cell line.

Authors:  J H Pope; M K Horne; E J Wetters
Journal:  Nature       Date:  1969-04-12       Impact factor: 49.962

6.  Epstein-Barr virus-induced viral and soluble complement-fixing antigens in Burkitt lymphoma cell cultures.

Authors:  P Gerber; D R Deal
Journal:  Proc Soc Exp Biol Med       Date:  1970-07

7.  Studies on leukocytes growing in continuous culture derived from normal human donors.

Authors:  P Gerber; J H Monroe
Journal:  J Natl Cancer Inst       Date:  1968-04       Impact factor: 13.506

8.  VIROGENIC HAMSTER TUMOR CELLS: INDUCTION OF VIRUS SYNTHESIS.

Authors:  P GERBER
Journal:  Science       Date:  1964-08-21       Impact factor: 47.728

9.  Herpes-type virus and chromosome marker in normal leukocytes after growth with irradiated Burkitt cells.

Authors:  W Henle; V Diehl; G Kohn; H Zur Hausen; G Henle
Journal:  Science       Date:  1967-09-01       Impact factor: 47.728

10.  Murine leukemia virus: high-frequency activation in vitro by 5-iododeoxyuridine and 5-bromodeoxyuridine.

Authors:  D R Lowy; W P Rowe; N Teich; J W Hartley
Journal:  Science       Date:  1971-10-08       Impact factor: 47.728

  10 in total
  69 in total

1.  Infection of human and rhesus lymphoblastoid cells with Herpesvirus macaca.

Authors:  P R Graze; I Royston
Journal:  Arch Virol       Date:  1975       Impact factor: 2.574

2.  Immunochemical characterization of Epstein-Barr virus-associated early and late antigens in n-butyrate-treated P3HR-1 cells.

Authors:  B Kallin; J Luka; G Klein
Journal:  J Virol       Date:  1979-12       Impact factor: 5.103

3.  Persistence of the cytomegalovirus genome in human cells.

Authors:  E S Mocarski; M F Stinski
Journal:  J Virol       Date:  1979-09       Impact factor: 5.103

4.  Identification of an intracellular precursor to DNA excreted by human lymphocytes.

Authors:  J C Rogers
Journal:  Proc Natl Acad Sci U S A       Date:  1976-09       Impact factor: 11.205

5.  Growth of B95-8 cells and expression of Epstein-Barr virus lytic phase in serum-free medium.

Authors:  J E Shaw; R G Petit; K Leung
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

6.  Cycloheximide induction of xenotropic type C virus from synchronized mouse cells: metabolic requirements for virus activation.

Authors:  J S Greenberger; S A Aaronson
Journal:  J Virol       Date:  1975-01       Impact factor: 5.103

7.  Viral and cellular DNA synthesis in nuclei from human lymphocytes transformed by Epstein-Barr virus.

Authors:  W C Benz; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

8.  The role of lipoproteins in EBV early antigen induction in Raji cells.

Authors:  M Simon; I Melzner; B Bültmann
Journal:  Arch Virol       Date:  1989       Impact factor: 2.574

9.  Rescue of Epstein-Barr virus from somatic cell hybrids of Burkitt lymphoblastoid cells.

Authors:  R Glaser; F Rapp
Journal:  J Virol       Date:  1972-08       Impact factor: 5.103

10.  Effects of 5-bromodeoxyuridine and 5-iododeoxyuridine on a latent herpes simplex virus infection.

Authors:  J Varani; J J Kelleher
Journal:  Antimicrob Agents Chemother       Date:  1975-07       Impact factor: 5.191

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