Literature DB >> 453818

Production of mycophenolic acid by Penicillium roqueforti strains.

P Lafont, J P Debeaupuis, M Gaillardin, J Payen.   

Abstract

Sixteen strains of Penicillium roqueforti Thom, isolated from blue-molded cheeses, were studied. In vitro, all of these strains produced mycophenolic acid, some on the order of 0.8 to 4 mg/g od dry culture. The greatest yields were obtained after 10 days of incubation of cultures at 15 degrees C. However, under some experimental conditions, mycophenolic acid was not alone responsible for the toxicity of culture extracts to chicken embryos.

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Year:  1979        PMID： 453818      PMCID： PMC243222          DOI： 10.1128/aem.37.3.365-368.1979

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  10 in total

1.  Long-term toxicity study of mycophenolic acid in rabbits.

Authors:  E Adams; G Todd; W Gibson
Journal:  Toxicol Appl Pharmacol       Date:  1975-12       Impact factor: 4.219

2.  Studies in the biochemistry of micro-organisms: The metabolic products of the Penicillium brevi-compactum series.

Authors:  P W Clutterbuck; A E Oxford; H Raistrick; G Smith
Journal:  Biochem J       Date:  1932       Impact factor: 3.857

3.  Toxin production by 50 strains of Penicillium used in the cheese industry.

Authors:  P Lafont; J Lafont; J Payen; E Chany; G Bertin; C Frayssinet
Journal:  Food Cosmet Toxicol       Date:  1976-04

4.  Studies in the biochemistry of micro-organisms. 86. The molecular constitution of mycophenolic acid, a metabolic product of Penicillium Brevi-compactum Dierckx. Part III. Further observations on the structural formula for mycophenolic acid.

Authors:  J H BIRKINSHAW; H RAISTRICK; D J ROSS
Journal:  Biochem J       Date:  1952-03       Impact factor: 3.857

5.  Antiviral and cytotoxic effects of mycophenolic acid.

Authors:  D N Planterose
Journal:  J Gen Virol       Date:  1969-06       Impact factor: 3.891

6.  [Mycotoxins produced by Aspergillus. Their action on the chick embryo].

Authors:  J Lafont; C Frayssinet
Journal:  C R Seances Soc Biol Fil       Date:  1969

7.  [Aflatoxin production by Aspergillus flavus Link in static cultures].

Authors:  P Lafont; J Lafont
Journal:  Ann Inst Pasteur (Paris)       Date:  1970-03

8.  Isolation and partial characterization of a mycotoxin from Penicillium roqueforti.

Authors:  R D Wei; P E Still; E B Smalley; H K Schnoes; F M Strong
Journal:  Appl Microbiol       Date:  1973-01

9.  The taxonomy of Penicillium species from fermented cheeses.

Authors:  R A Samson; C Eckardt; R Orth
Journal:  Antonie Van Leeuwenhoek       Date:  1977       Impact factor: 2.271

10.  Study of conditions of production of roquefortine and other metabolites of Penicillin roqueforti.

Authors:  P M Scott; B P Kennedy; J Harwig; B J Blanchfield
Journal:  Appl Environ Microbiol       Date:  1977-02       Impact factor: 4.792
  10 in total
  9 in total

1.  Strain-Specific Synthesis of Mycophenolic Acid by Penicillium roqueforti in Blue-Veined Cheese.

Authors:  G Engel; K E von Milczewski; D Prokopek; M Teuber
Journal:  Appl Environ Microbiol       Date:  1982-05       Impact factor: 4.792

2.  Optimization of submerged fermentation conditions for immunosuppressant mycophenolic acid production by Penicillium roqueforti isolated from blue-molded cheeses: enhanced production by ultraviolet and gamma irradiation.

Authors:  Ahmed A Ismaiel; Ashraf S Ahmed; El-Sayed R El-Sayed
Journal:  World J Microbiol Biotechnol       Date:  2014-06-14       Impact factor: 3.312

3.  Antagonism against Rhizoctonia solani and fungitoxic metabolite production by some Penicillium isolates.

Authors:  R Nicoletti; M De Stefano; S De Stefano; A Trincone; F Marziano
Journal:  Mycopathologia       Date:  2004-11       Impact factor: 2.574

4.  Production of Mycophenolic Acid by a Newly Isolated Indigenous Penicillium glabrum.

Authors:  Fatemeh Mahmoudian; Atefeh Sharifirad; Bagher Yakhchali; Saham Ansari; Seyed Safa-Ali Fatemi
Journal:  Curr Microbiol       Date:  2021-05-21       Impact factor: 2.188

5.  Production of mycophenolic acid by Penicillium brevicompactum-A comparison of two methods of optimization.

Authors:  Gopal Patel; Mahesh D Patil; Surbhi Soni; Taresh P Khobragade; Yusuf Chisti; Uttam Chand Banerjee
Journal:  Biotechnol Rep (Amst)       Date:  2016-08-04

6.  Secondary Metabolites from Penicillium roqueforti, A Starter for the Production of Gorgonzola Cheese.

Authors:  Lisa Vallone; Alberto Giardini; Gabriella Soncini
Journal:  Ital J Food Saf       Date:  2014-09-11

7.  Identification and Functional Analysis of the Mycophenolic Acid Gene Cluster of Penicillium roqueforti.

Authors:  Abdiel Del-Cid; Carlos Gil-Durán; Inmaculada Vaca; Juan F Rojas-Aedo; Ramón O García-Rico; Gloria Levicán; Renato Chávez
Journal:  PLoS One       Date:  2016-01-11       Impact factor: 3.240

Review 8.  PR Toxin - Biosynthesis, Genetic Regulation, Toxicological Potential, Prevention and Control Measures: Overview and Challenges.

Authors:  Manish K Dubey; Mohd Aamir; Manish S Kaushik; Saumya Khare; Mukesh Meena; Surendra Singh; Ram S Upadhyay
Journal:  Front Pharmacol       Date:  2018-03-29       Impact factor: 5.810

9.  Toxic Indoor Air Is a Potential Risk of Causing Immuno Suppression and Morbidity-A Pilot Study.

Authors:  Kirsi Vaali; Marja Tuomela; Marika Mannerström; Tuula Heinonen; Tamara Tuuminen
Journal:  J Fungi (Basel)       Date:  2022-01-21
  9 in total

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