Literature DB >> 4525281

Transcription of polydeoxythymidylate sequences in the genome of the cellular slime mold, Dictyostelium discoideum.

A Jacobson, R A Firtel, H Lodish.   

Abstract

Messenger RNA of the cellular slime mold, Dictyostelium discoideum, contains about equimolar amounts of two classes of poly(adenylic acid) [poly(A)]; one is about 25 nucleotides long and the second about 100 nucleotides long. At least half of the messenger RNA molecules contain one sequence each of poly(A)(25) and poly(A)(100); both poly(A) sequences are located near the 3' end of messenger RNA, and the kinetics of their appearance on messenger RNA precursor indicates that poly(A)(25) is added before poly(A)(100). Dictyostelium nuclear DNA contains 14,000-15,000 sequences of poly(dT)(25) which could code for the smaller poly(A) residues. The poly(A)(100) must be added post-transcriptionally. The poly(dT)(25) sequences are interspersed throughout the genome and may well represent transcription termination regions.

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Year:  1974        PMID: 4525281      PMCID: PMC388285          DOI: 10.1073/pnas.71.5.1607

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  26 in total

1.  Nucleotide sequence of a ribonucleic acid transcribed in vitro from lambda phage deoxyribonucleic acid.

Authors:  P Lebowitz; S M Weissman; C M Radding
Journal:  J Biol Chem       Date:  1971-08-25       Impact factor: 5.157

2.  Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication.

Authors:  L Philipson; R Wall; G Glickman; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1971-11       Impact factor: 11.205

3.  Thermal transitions in mixtures of polydeoxyribodinucleotides.

Authors:  F N Hayes; E H Lilly; R L Ratliff; D A Smith; D L Williams
Journal:  Biopolymers       Date:  1970       Impact factor: 2.505

4.  Electrophoretic separation of viral nucleic acids on polyacrylamide gels.

Authors:  D H Bishop; J R Claybrook; S Spiegelman
Journal:  J Mol Biol       Date:  1967-06-28       Impact factor: 5.469

5.  An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA.

Authors:  J E Darnell; R Wall; R J Tushinski
Journal:  Proc Natl Acad Sci U S A       Date:  1971-06       Impact factor: 11.205

6.  Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture.

Authors:  D J Watts; J M Ashworth
Journal:  Biochem J       Date:  1970-09       Impact factor: 3.857

7.  Messenger and heterogeneous nuclear RNA in HeLa cells: differential inhibition by cordycepin.

Authors:  S Penman; M Rosbash; M Penman
Journal:  Proc Natl Acad Sci U S A       Date:  1970-12       Impact factor: 11.205

8.  Physical and chemical characterization of two- and three-stranded adenine-thymine and adenine-uracil homopolymer complexes.

Authors:  M Riley; B Maling
Journal:  J Mol Biol       Date:  1966-09       Impact factor: 5.469

9.  Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA.

Authors:  J E Darnell; L Philipson; R Wall; M Adesnik
Journal:  Science       Date:  1971-10-29       Impact factor: 47.728

10.  RNA in cytoplasmic and nuclear fractions of cellular slime mold amebas.

Authors:  S M Cocucci; M Sussman
Journal:  J Cell Biol       Date:  1970-05       Impact factor: 10.539

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  14 in total

1.  Kinetics of induced and repressed enzyme synthesis in Saccharomyces cerevisiae.

Authors:  R P Lawther; T G Cooper
Journal:  J Bacteriol       Date:  1975-03       Impact factor: 3.490

2.  The binding of poly (rA) and poly (rU) to denatured DNA. II. Studies with natural DNAs.

Authors:  J N Mol; P Borst
Journal:  Nucleic Acids Res       Date:  1976-04       Impact factor: 16.971

3.  Poly(adenylic acid) sequences in the RNA of Caulobacter crescenus.

Authors:  N Ohta; M Sanders; A Newton
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

4.  Sequence organization in Dictyostelium: unique structure at the 5'-ends of protein coding genes.

Authors:  A R Kimmel; R A Firtel
Journal:  Nucleic Acids Res       Date:  1983-01-25       Impact factor: 16.971

5.  Repeating structure of cytoplasmic poly(A)-ribonucleoprotein.

Authors:  B W Baer; R D Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

6.  RNA synthesis in cells infected with herpes simplex virus. XII. Sequence complexity and properties of RNA differing in extent of adenylation.

Authors:  S Silvertien; R Millette; P Jones; B Roizman
Journal:  J Virol       Date:  1976-06       Impact factor: 5.103

7.  The presence of (dA.dT)20-25 tracts in the DNA of primitive eukaryotes.

Authors:  J N Mol; R A Flavell; P Borst
Journal:  Nucleic Acids Res       Date:  1976-09       Impact factor: 16.971

8.  Structure of polyadenylic acid in the ribonucleic acid of Saccharomyces cerevisiae.

Authors:  S L Phillips; C Tse; I Serventi; N Hynes
Journal:  J Bacteriol       Date:  1979-05       Impact factor: 3.490

9.  The binding of poly(rA) and poly(rU) to denatured DNA. I. Model studies with homopolymers.

Authors:  J N Mol; P Borst
Journal:  Nucleic Acids Res       Date:  1976-04       Impact factor: 16.971

10.  Interaction of anthracyclines with DNA and chromosomes.

Authors:  F P Johnston; K F Jorgenson; C C Lin; J H van de Sande
Journal:  Chromosoma       Date:  1978-08-28       Impact factor: 4.316

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