Literature DB >> 4510282

Biological activities of synthetic peptides corresponding to fragments of and to the entire sequence of the vasoactive intestinal peptide.

M Bodanszky, Y S Klausner, S I Said.   

Abstract

An octacosapeptide with the entire sequence proposed for the newly isolated vasoactive intestinal polypeptide was synthesized and had the expected biological properties. Synthetic peptides corresponding to the C-terminal hendeca-, tetradeca-, pentadeca-, and docosapeptide sequences of the vasoactive intestinal polypeptide showed activities that increased with increasing chain length.

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Year:  1973        PMID: 4510282      PMCID: PMC433264          DOI: 10.1073/pnas.70.2.382

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  5 in total

1.  Effects on smooth muscle preparations of unidentified vasoactiv peptides from intestine and lung.

Authors:  P J Piper; S I Said; J R Vane
Journal:  Nature       Date:  1970-03-21       Impact factor: 49.962

2.  Isolation from porcine-intestinal wall of a vasoactive octacosapeptide related to secretin and to glucagon.

Authors:  S I Said; V Mutt
Journal:  Eur J Biochem       Date:  1972-07-13

3.  A gastric inhibitory polypeptide. II. The complete amino acid sequence.

Authors:  J C Brown; J R Dryburgh
Journal:  Can J Biochem       Date:  1971-08

4.  Polypeptide with broad biological activity: isolation from small intestine.

Authors:  S I Said; V Mutt
Journal:  Science       Date:  1970-09-18       Impact factor: 47.728

5.  Structure of porcine secretin. The amino acid sequence.

Authors:  V Mutt; J E Jorpes; S Magnusson
Journal:  Eur J Biochem       Date:  1970-09
  5 in total
  31 in total

1.  Hormonal control of gastrointestinal motility.

Authors:  R F Harvey
Journal:  Am J Dig Dis       Date:  1975-06

2.  Effects of epithelium removal on relaxation of airway smooth muscle induced by vasoactive intestinal peptide and electrical field stimulation.

Authors:  S G Farmer; J Togo
Journal:  Br J Pharmacol       Date:  1990-05       Impact factor: 8.739

3.  Vasoactive intestinal peptide stimulation of human renal adenylate cyclase in vitro.

Authors:  B G Charlton; D E Neal; N L Simmons
Journal:  J Physiol       Date:  1990-04       Impact factor: 5.182

4.  Vasoactive intestinal polypeptide: specific binding to rat brain membranes.

Authors:  D P Taylor; C B Pert
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

5.  Cyclical release of vasoactive intestinal polypeptide (VIP) from a pancreatic islet cell apudoma.

Authors:  B L Devine; H A Carmichael; R I Russell; S N Joffe
Journal:  Postgrad Med J       Date:  1978-08       Impact factor: 2.401

6.  Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications.

Authors:  J Fahrenkrug; U Haglund; M Jodal; O Lundgren; L Olbe; O B de Muckadell
Journal:  J Physiol       Date:  1978-11       Impact factor: 5.182

Review 7.  Progress report. Radioimmunoassay of intestinal hormones.

Authors:  S R Bloom
Journal:  Gut       Date:  1974-06       Impact factor: 23.059

Review 8.  The Bayliss-Starling lecture 1973. The gastrointestinal hormones: a review of recent advances.

Authors:  R A Gregory
Journal:  J Physiol       Date:  1974-08       Impact factor: 5.182

9.  Interactions between autonomic nerves and endocrine cells of the gastroenteropancreatic system.

Authors:  P H Smith; Katherine L Madson
Journal:  Diabetologia       Date:  1981-03       Impact factor: 10.122

10.  Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurons.

Authors:  L I Larsson; J Fahrenkrug; O Schaffalitzky De Muckadell; F Sundler; R Håkanson; J R Rehfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1976-09       Impact factor: 11.205

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