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Literature DB >> 4508306

Mammalian cells with altered forms of RNA polymerase II.

Abstract

Mutants of Chinese hamster ovary cells that are resistant to alpha-amanitin can be isolated. At least some of these mutants contain an altered form of DNA-dependent RNA polymerase II, as indicated by its resistance to alpha-amanitin. These results indicate that mutation to alpha-amanitin resistance involves a change of a structural gene.

Entities: Chemical Species

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Year: 1972 PMID： 4508306 PMCID： PMC389717 DOI： 10.1073/pnas.69.11.3119

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

18 in total

1. The effect of rifampicin on mitochondrial RNA polymerase from rat liver.

Authors: M N. Gadaleta; M Greco; C Saccone
Journal: FEBS Lett Date: 1970-09-18 Impact factor: 4.124

2. Alpha-amanitin: a specific inhibitor of one of two DNA-pendent RNA polymerase activities from calf thymus.

Authors: C Kedinger; M Gniazdowski; J L Mandel; F Gissinger; P Chambon
Journal: Biochem Biophys Res Commun Date: 1970-01-06 Impact factor: 3.575

Review 3. Poisonous principles of mushrooms of the genus Amanita. Four-carbon amines acting on the central nervous system and cell-destroying cyclic peptides are produced.

Authors: T Wieland
Journal: Science Date: 1968-03-01 Impact factor: 47.728

4. Mutation rates in cells at different ploidy levels.

Authors: M Harris
Journal: J Cell Physiol Date: 1971-10 Impact factor: 6.384

5. Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms.

Authors: R G Roeder; W J Rutter
Journal: Nature Date: 1969-10-18 Impact factor: 49.962

6. Specific action of alpha-amanitin on mammalian RNA polymerase protein.

Authors: S T Jacob; E M Sajdel; H N Munro
Journal: Nature Date: 1970-01-03 Impact factor: 49.962

7. Different responses of soluble whole nuclear RNA polymerase and soluble nucleolar RNA polymerase to divalent cations and to inhibition by alpha-amanitin.

Authors: S T Jacob; E M Sajdel; H N Munro
Journal: Biochem Biophys Res Commun Date: 1970-02-20 Impact factor: 3.575

8. Two types of ribosome in mouse-hamster hybrid cells.

Authors: C P Stanners; G L Eliceiri; H Green
Journal: Nat New Biol Date: 1971-03-10

9. RNA polymerases of maize: nuclear RNA polymerases.

Authors: G C Strain; K P Mullinix; L Bogorad
Journal: Proc Natl Acad Sci U S A Date: 1971-11 Impact factor: 11.205

10. Puromycin resistance in haploid and heteroploid frog cells: gene or membrane determined?

Authors: L Mezger-Freed
Journal: J Cell Biol Date: 1971-12 Impact factor: 10.539

38 in total

Review 1. Amanitins in virus research.

Authors: G Campadelli-Fiume
Journal: Arch Virol Date: 1978 Impact factor: 2.574

2. DNA-mediated transfer of an RNA polymerase II gene: reversion of the temperature-sensitive hamster cell cycle mutant TsAF8 by mammalian DNA.

Authors: C J Ingles; M Shales
Journal: Mol Cell Biol Date: 1982-06 Impact factor: 4.272

Mammalian cells with altered forms of RNA polymerase II.

1. The effect of rifampicin on mitochondrial RNA polymerase from rat liver.

2. Alpha-amanitin: a specific inhibitor of one of two DNA-pendent RNA polymerase activities from calf thymus.

Review 3. Poisonous principles of mushrooms of the genus Amanita. Four-carbon amines acting on the central nervous system and cell-destroying cyclic peptides are produced.

4. Mutation rates in cells at different ploidy levels.

5. Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms.

6. Specific action of alpha-amanitin on mammalian RNA polymerase protein.

7. Different responses of soluble whole nuclear RNA polymerase and soluble nucleolar RNA polymerase to divalent cations and to inhibition by alpha-amanitin.

8. Two types of ribosome in mouse-hamster hybrid cells.

9. RNA polymerases of maize: nuclear RNA polymerases.

10. Puromycin resistance in haploid and heteroploid frog cells: gene or membrane determined?

Review 1. Amanitins in virus research.

2. DNA-mediated transfer of an RNA polymerase II gene: reversion of the temperature-sensitive hamster cell cycle mutant TsAF8 by mammalian DNA.

3. Hamster alpha-amanitine-resistant RNA polymerase II able to transcribe polyoma virus genome in somatic cell hybrids.

4. Transfer of codominant markers by isolated metaphase chromosomes in Chinese hamster ovary cells.

5. Temperature-sensitive RNA polymerase II mutations in Chinese hamster ovary cells.

6. A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA synthetase.

7. Variants of mouse myeloma cells that produce short immunoglobulin heavy chains.

Review 8. Quantitative genetic analysis of tumor progression.

9. Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase B.

10. Altered sensitivity of Rous sarcoma virus transformed cells to inhibition of RNA synthesis by alpha-amanitin.