Literature DB >> 4506068

Control of the rat pineal gland by light spectra.

D P Cardinali, F Larin, R J Wurtman.   

Abstract

Control of pineal hydroxyindole-O-methyl transferase (S-adenosylmethionine:N-acetylserotonin-O-methyl transferase; EC 2.1.1.4) by light spectra was determined by placing groups of rats previously housed in continuous darkness under one of seven light sources for 96 hr; rats were exposed to the same intensity of irradiation. Activity of the enzyme was lowest in rats maintained under green light (lambda peak = 530 nm); blue and yellow light were somewhat less effective; red and ultraviolet light did not significantly lower the enzyme activity. The suppression of pineal hydroxyindole-O-methyl transferase by full-spectrum light sources could be correlated with the proportions of their spectral outputs in the blue-green-yellow range. These observations suggest that the retinal photopigment that mediates pineal responses to light in rats is rhodopsin or another compound with similar absorption properties.

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Year:  1972        PMID： 4506068      PMCID： PMC426855          DOI： 10.1073/pnas.69.8.2003

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  11 in total

1.  Purification and properties of hydroxyindole-O-methyl transferase.

Authors:  J AXELROD; H WEISSBACH
Journal:  J Biol Chem       Date:  1961-01       Impact factor: 5.157

2.  CONTROL OF HYDROXYINDOLE O-METHYLTRANSFERASE ACTIVITY IN THE RAT PINEAL GLAND BY ENVIRONMENTAL LIGHTING.

Authors:  J AXELROD; R J WURTMAN; S H SNYDER
Journal:  J Biol Chem       Date:  1965-02       Impact factor: 5.157

3.  Synthesis and bleaching of rhodopsin.

Authors:  G WALD; P K BROWN
Journal:  Nature       Date:  1956-01-28       Impact factor: 49.962

Review 4.  The mammalian pineal as a neuroendocrine transducer.

Authors:  R J Wurtman; F Anton-Tay
Journal:  Recent Prog Horm Res       Date:  1969

5.  Indole metabolism in the pineal gland: a circadian rhythm in N-acetyltransferase.

Authors:  D C Klein; J L Weller
Journal:  Science       Date:  1970-09-11       Impact factor: 47.728

6.  A melatonin rhythm persists in rat pineals in darkness.

Authors:  C L Ralph; D Mull; H J Lynch; L Hedlund
Journal:  Endocrinology       Date:  1971-12       Impact factor: 4.736

7.  Environmental lighting and neuroendocrine function: relationship between spectrum of light source and gonadal growth.

Authors:  R J Wurtman; J Weisel
Journal:  Endocrinology       Date:  1969-12       Impact factor: 4.736

8.  VISUAL PIGMENTS IN SINGLE RODS AND CONES OF THE HUMAN RETINA. DIRECT MEASUREMENTS REVEAL MECHANISMS OF HUMAN NIGHT AND COLOR VISION.

Authors:  P K BROWN; G WALD
Journal:  Science       Date:  1964-04-03       Impact factor: 47.728

9.  Retinal localization of the hydroxyindole-O-methyl transferase (HIOMT) in the rat.

Authors:  D P Cardinali; J M Rosner
Journal:  Endocrinology       Date:  1971-07       Impact factor: 4.736

10.  MELATONIN SYNTHESIS IN THE PINEAL GLAND: CONTROL BY LIGHT.

Authors:  R J WURTMAN; J AXELROD; L S PHILLIPS
Journal:  Science       Date:  1963-11-22       Impact factor: 47.728
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  9 in total

1.  Divergent photic thresholds in the non-image-forming visual system: entrainment, masking and pupillary light reflex.

Authors:  Matthew P Butler; Rae Silver
Journal:  Proc Biol Sci       Date:  2010-09-22       Impact factor: 5.349

2.  Relevance of Electrical Light on Circadian, Neuroendocrine, and Neurobehavioral Regulation in Laboratory Animal Facilities.

Authors:  John P Hanifin; Robert T Dauchy; David E Blask; Steven M Hill; George C Brainard
Journal:  ILAR J       Date:  2020-10-19

3.  The influence of light of different wavelengths on the methylating capacity of the pineal gland of male golden hamsters in relation to reproduction.

Authors:  J van Benthem; A C Steinen; M C Sommer; J De Koning; I Ebels; M G Balemans
Journal:  J Neural Transm       Date:  1989       Impact factor: 3.575

Review 4.  Melatonin and Multiple Sclerosis: From Plausible Neuropharmacological Mechanisms of Action to Experimental and Clinical Evidence.

Authors:  Mahshid Yeganeh Salehpour; Adriano Mollica; Saeideh Momtaz; Nima Sanadgol; Mohammad Hosein Farzaei
Journal:  Clin Drug Investig       Date:  2019-07       Impact factor: 2.859

5.  The influence of some pteridines on pineal 5-methoxyindole synthesis in male Wistar rats periodically exposed to either white or green light.

Authors:  M G Balemans; I Ebels; H G Hendriks; M van Berlo; A de Moreé
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

6.  Changes in the circadian rhythmicity of N- and O-acetyltransferase activities in the pineal gland of 38 day old male wistar rats when examined under white, red and green light.

Authors:  M G Balemans; I Smith; G F de Reuver
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

7.  Changes in the circadian rhythmicity of hydroxyindole-O-methyl transferase (HIOMT) activity in the synthesis of 5-methoxyindoles in the pineal gland of 28 day old male Wistar rats exposed to white, red and green light.

Authors:  M G Balemans; I Ebels; H G Hendriks; M F van Berlo
Journal:  J Neural Transm       Date:  1982       Impact factor: 3.575

8.  Effects of melatonin treatment and environmental lighting on the ultrastructural appearence, melatonin synthesis, norepinephrine turnover and microtubule protein content of the rat pineal gland.

Authors:  F Freire; D P Cardinali
Journal:  J Neural Transm       Date:  1975       Impact factor: 3.575

9.  Neither the pituitary gland nor the sympathetic nervous system is responsible for eliciting the large drop in elevated rat pineal melatonin levels due to swimming.

Authors:  M E Troiani; R J Reiter; M G Tannenbaum; M Puig-Domingo; J M Guerrero; A Menendez-Pelaez
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575
  9 in total

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