| Literature DB >> 446682 |
L E Kalbermann, I Szijan, J A Burdman.
Abstract
We investigated the relationship between prolactin content and DNA replication in the anterior pituitary gland. Thymidine incorporation in pregnant rats is significantly lower than in virgin controls. This is accompanied by a decreased activity of DNA polymerase. Sulpiride administration to pregnant rats enhances thymidine incorporation to levels similar to virgin controls. The results indicate a negative feedback between prolactin content and DNA synthesis in the rat anterior pituitary gland.Entities:
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Year: 1979 PMID: 446682 DOI: 10.1007/bf01960401
Source DB: PubMed Journal: Experientia ISSN: 0014-4754