Literature DB >> 1121507

Acute and chronic effects of sulpride on serum prolactin and gonadotropin levels in castrated male rats (38581).

L Debeljuk, R Rozados, H Daskal, V Velez, A M Mancini.   

Abstract

The effect of the acute or chronic administration of sulpiride on serum prolactin and gonadotropin levels was studied in castrated male rats. Sulpiride administered in acute intravenous injections induced a quick increase in serum prolactin levels and no significant changes in serum gonadotropins. The peak in serum prolactin was observed 30 min after the injection of sulpiride, with a decrease of serum prolactin levels at 60 and 120 min. The subcutaneous administration of sulpiride for 13 days induced a significant increase in serum prolactin levels at the end of the treatment, and no significant changes in serum FSH and LH levels.

Entities:  

Mesh:

Substances:

Year:  1975        PMID: 1121507     DOI: 10.3181/00379727-148-38581

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  6 in total

1.  Regional distribution of sultopride and sulpiride in rat brain measured by radioimmunoassay.

Authors:  A Mizuchi; N Kitagawa; Y Miyachi
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

2.  Effects of chronic sultopride treatment on endocrine systems in psychotic women.

Authors:  Y Miyachi; A Mizuchi; H Hamano; K Sarai
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

3.  DNA synthesis in the pituitary gland of the rat: effect of sulpiride and clomiphene.

Authors:  J A Burdman; I Szijan; G A Jahn; G Machiavelli; L E Kalbermann
Journal:  Experientia       Date:  1979-09-15

4.  Cell proliferation in the rat pituitary gland: a mechanism of control in prolactin cells.

Authors:  L E Kalbermann; I Szijan; J A Burdman
Journal:  Experientia       Date:  1979-05-15

5.  Unresponsiveness of prolactin to repeated injection of sulpiride in man.

Authors:  H Cohen; M Pugeat; J Tourniaire; J Bertrand
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

6.  Effects of sulpiride on prolactin and mRNA levels of steroid 5alpha-reductase isozymes in adult rat brain.

Authors:  Pilar Sánchez; Jesús M Torres; Pablo Vílchez; Raimundo G Del Moral; Esperanza Ortega
Journal:  Neurochem Res       Date:  2007-10-17       Impact factor: 3.996

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.