Literature DB >> 442836

[Behaviour of p-nitrophenol-glucuronide in hydrolysis with mineral acids (author's transl)].

S Goenechea, K Kobbe, K J Goebel.   

Abstract

The behaviour of p-nitrophenol and synthetic p-nitrophenol-glucuronide with mineral acids has been investigated. With sulfuric acid (33%) about 93% of the glucuronide derivative have been hydrolysed; the solution was heated in open vessel for 15 sec. With hydrochloric acid (6%) only about 65% of the conjugated p-nitrophenol have been converted to the free form. No losses were detected, when free p-nitrophenol was treated under the same conditions. Three other methods of hydrolysis have been applied.

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Year:  1979        PMID: 442836     DOI: 10.1007/bf00201313

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  5 in total

1.  [Quantitative identification of 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepine-2-one in plasma at single and prolonged administration].

Authors:  G Kamm; R Kelm
Journal:  Arzneimittelforschung       Date:  1969-10

2.  [Rapid detection of methaqualone metabolites and of the chlordiazepoxides in urine].

Authors:  U Mang
Journal:  Z Klin Chem Klin Biochem       Date:  1970-05

3.  [Behavior of morphine-3-glucuronide in hydrolysis with hydrochloric acid].

Authors:  S Goenechea; J Goebel K
Journal:  Beitr Gerichtl Med       Date:  1978

4.  [Rapid test for p-nitrophenol in urine in the diagnosis of E-605 poisoning].

Authors:  K Deinzer
Journal:  Z Klin Chem Klin Biochem       Date:  1966-03

5.  [The behaviour of codeine and codeine-6-glucuronide in hydrolysis with hydrochloric acid (author's transl)].

Authors:  S Goenechea; K Kobbe; K J Goebel
Journal:  Arzneimittelforschung       Date:  1978
  5 in total
  4 in total

1.  Determination of p-nitrophenol in serum and urine by enzymatic and non-enzymatic conjugate hydrolysis and HPLC. Application after parathion intoxication.

Authors:  P Michalke
Journal:  Z Rechtsmed       Date:  1984

2.  [Behaviour of hydroxymethyl-methaqualone-glucuronide in hydrolysis with hydrochloric acid (author's transl)].

Authors:  S Goenechea; K Kobbe; K J Goebel
Journal:  Z Rechtsmed       Date:  1980

3.  [Sensitive determination of p-nitrophenol in blood and urine by HPLC after E 605 intoxication (author's transl)].

Authors:  P Michalke
Journal:  Z Rechtsmed       Date:  1982

4.  [Cleavage of synthetic pentazocine glucuronide with hydrochloric acid].

Authors:  S Goenechea; G Rücker; M Langer; M Neugebauer
Journal:  Z Rechtsmed       Date:  1985
  4 in total

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