Literature DB >> 7102114

[Sensitive determination of p-nitrophenol in blood and urine by HPLC after E 605 intoxication (author's transl)].

P Michalke.   

Abstract

p-Nitrophenol, the main metabolite of parathion metabolism can be quantified by high performance liquid chromatography (HPLC) following very simple preparation of small quantities of blood the urine. Determination is carried out by UV detection at 315 nm following separation on a RP 18 column. Detection limits are 5-10 ng/ml serum and 50-100 ng/ml urine. levels of p-nitrophenol in blood and urine after survival from parathion intoxication are demonstrated.

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Year:  1982        PMID： 7102114     DOI： 10.1007/BF00200724

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN： 0044-3433


  10 in total

1.  Exposure to parathion. Measurement by blood cholinesterase level and urinary p-nitrophenol excretion.

Authors:  J D ARTERBERRY; W F DURHAM; J W ELLIOTT; H R WOLFE
Journal:  Arch Environ Health       Date:  1961-10

2.  [Chemical and toxicological determination of E 605 Bayer and other insecticides of the thiophosphoric acid series].

Authors:  T HAAG; H KAISER
Journal:  Arch Pharm Ber Dtsch Pharm Ges       Date:  1956 Sep-Oct

3.  [Behaviour of p-nitrophenol-glucuronide in hydrolysis with mineral acids (author's transl)].

Authors:  S Goenechea; K Kobbe; K J Goebel
Journal:  Z Rechtsmed       Date:  1979-04-27

4.  Determination of acetylcholine, nitrostigmine and acetylcholinesterase activity in four patients with severe nitrostigmine (E 605 forte) intoxication.

Authors:  S Okonek; H Kilbinger
Journal:  Arch Toxicol       Date:  1974       Impact factor: 5.153

5.  [New method for purification and determination of urinary p-nitrophenol].

Authors:  P Cenci; G Cavazzini
Journal:  Med Lav       Date:  1972 Jan-Feb       Impact factor: 1.275

6.  [Gas chromatography determination of insecticides in blood with the halogenphosphorus detector].

Authors:  J Bäumler; S Rippstein
Journal:  Arch Toxikol       Date:  1969

7.  Confirmation of paranitrophenol as a human urinary metabolite at the nanogram level.

Authors:  K W Kirby; J E Keiser; J Groene; E F Slach
Journal:  J Agric Food Chem       Date:  1979 Jul-Aug       Impact factor: 5.279

8.  [Rapid test for p-nitrophenol in urine in the diagnosis of E-605 poisoning].

Authors:  K Deinzer
Journal:  Z Klin Chem Klin Biochem       Date:  1966-03

9.  [Detection and determination of parathion and p-nitrophenol in biological material by reverse-phase-high-power-liquid chromatography (author's transl)].

Authors:  K Harzer; R Barchet
Journal:  Arch Toxicol       Date:  1975-09-05       Impact factor: 5.153

10.  [Gas chromatography determination of nitrostigmine (parathion) in plasma without extraction procedures].

Authors:  G Boelcke
Journal:  Arch Toxikol       Date:  1970
  10 in total
  2 in total

1.  Determination of p-nitrophenol in serum and urine by enzymatic and non-enzymatic conjugate hydrolysis and HPLC. Application after parathion intoxication.

Authors:  P Michalke
Journal:  Z Rechtsmed       Date:  1984

2.  Urinary excretion kinetics of p-nitrophenol following oral administration of parathion in the rabbit.

Authors:  M J Peña-Egido; E L Mariño-Hernandez; C Santos-Buelga; J C Rivas-Gonzalo
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153
  2 in total

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