Literature DB >> 4403140

Aryl hydrocarbon (benzopyrene) hydroxylase is stimulated in human lymphocytes by mitogens and benz(a)anthracene.

J P Whitlock, H L Cooper, V H Gelboin.   

Abstract

A mixed-function oxidase that requires reduced nicotinamide adenine dinucleotide phosphate, is carbon monoxide sensitive, and is drug-metabolizing is present in human lymphocytes and is increased to different levels by treatment with phytohemagglutinin, pokeweed mitogen, and a polycyclic hydrocarbon.

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Year:  1972        PMID： 4403140     DOI： 10.1126/science.177.4049.618

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

1.  Effect of adamantanone derivative possessing anti-HIV properties on the redox processes in the cytochrome P-450 system.

Authors:  I E Kovalev; N V Shipulina
Journal:  Dokl Biochem Biophys       Date:  2001 May-Jun       Impact factor: 0.788

2.  Distribution and inducibility of a P450I activity in cellular components of the avian immune system.

Authors:  N A Lorr; K A Golemboski; R A Hemendinger; R R Dietert; S E Bloom
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153

3.  Use of human peripheral blood lymphocytes to measure DNA binding capacity of chemical carcinogens.

Authors:  R C Gupta; K Earley; S Sharma
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

4.  Benzo(a)pyrene hydroxylase activity in human bronchial mucus.

Authors:  A Kapoor; J K Batra; U K Luthra; R C Jain; T A Venkitasubramanian; H G Raj
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1986 Jan-Mar       Impact factor: 2.441

5.  Activation of xenobiotics by monooxygenases: cultures of mammalian cells as analytical tool.

Authors:  F J Wiebel; S Brown; H L Waters; J K Selkirk
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

6.  Glutathione S-transferase in human lymphoid cell lines and fractionated peripheral leucocytes.

Authors:  N Kaplowitz; C Spina; M Graham; J Kuhlenkamp
Journal:  Biochem J       Date:  1978-03-01       Impact factor: 3.857

7.  Inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes: a study of repeatability.

Authors:  K A Fletcher; D A Evans; M V Canning
Journal:  J Med Genet       Date:  1978-06       Impact factor: 6.318

8.  Release of lymphotoxin by control and chemical carcinogen-treated lymphocyte cultures derived from black healthy subjects and cancer patients.

Authors:  L J Alfred; N Venkatesan; A K Mandal; G Gill; M Richardson; C Williams; C Bradley
Journal:  J Natl Med Assoc       Date:  1982-08       Impact factor: 1.798

9.  Phenotyping of cytochromes P-450 in human tissues with monoclonal antibodies.

Authors:  T Fujino; S S Park; D West; H V Gelboin
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

10.  Induction of aryl hydrocarbon hydroxylase in human pulmonary alveolar macrophages by cigarette smoking.

Authors:  E T Cantrell; G A Warr; D L Busbee; R R Martin
Journal:  J Clin Invest       Date:  1973-08       Impact factor: 14.808
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