Literature DB >> 4372390

Effect of chemically modified 70S RNA from avian myeloblastosis virus (AMV) upon the activity of AMV DNA polymerase.

T S Papas, J G Chirikjian, T W Pry, J G Massicot, R D Irwin, M A Chirigos.   

Abstract

Adenine residues of 70S avian myeloblastosis virus (AMV) RNA are modified when reacted with chloroacetaldehyde. This modification introduces characteristic fluorescent epsilon-adenosine (epsilonA) probes which were used to monitor the reaction. Under suitable conditions, modified 70S(epsilonA) RNA was maintained intact and was inactive as a template for the AMV DNA polymerase. Furthermore, it inhibited the reaction catalyzed by AMV polymerase when 70S RNA was used as template-primer and had no effect on the two tested bacterial polymerases. Protection against the 70S (epsilonA) RNA inhibition was observed when 70S RNA was primed with oligo(dT) indicating preference of the polymerase for the oligo(dT) primed regions.

Entities:  

Mesh：

Substances：

Year:  1974        PMID： 4372390      PMCID： PMC355627     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  11 in total

1.  Synthesis and properties of a new fluorescent polynucleotide, poly(1,N6-ethenoadenylic acid).

Authors:  H Lehrach; K H Scheit
Journal:  Biochim Biophys Acta       Date:  1973-04-21

2.  Fluorescent adenosine and cytidine derivatives.

Authors:  J R Barrio; J A Secrist; N J Leonard
Journal:  Biochem Biophys Res Commun       Date:  1972-01-31       Impact factor: 3.575

3.  RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template.

Authors:  A J Faras; J M Taylor; W E Levinson; H M Goodman; J M Bishop
Journal:  J Mol Biol       Date:  1973-09-05       Impact factor: 5.469

4.  Purification of the DNA polymerase of avian myeloblastosis virus.

Authors:  D L Kacian; K F Watson; A Burny; S Spiegelman
Journal:  Biochim Biophys Acta       Date:  1971-09-24

Review 5.  RNA-dependent DNA polymerase in viruses and cells: views on the current state.

Authors:  R C Gallo
Journal:  Blood       Date:  1972-01       Impact factor: 22.113

6.  Viral DNA-dependent DNA polymerase and the properties of thymidine labelled material in virions of an oncogenic RNA virus.

Authors:  J Ríman; G S Beaudreau
Journal:  Nature       Date:  1970-10-31       Impact factor: 49.962

7.  Effects of polyadenylic acids on functions of murine RNA tumor viruses.

Authors:  R W Tennant; J G Farrelly; J N Ihle; B C Pal; F T Kenney; A Brown
Journal:  J Virol       Date:  1973-12       Impact factor: 5.103

8.  Inhibition of the DNA polymerase of Rauscher leukemia virus by single-stranded polyribonucleotides.

Authors:  F W Tuominen; F T Kenney
Journal:  Proc Natl Acad Sci U S A       Date:  1971-09       Impact factor: 11.205

9.  Distinguishing reverse transcriptase of an RNA tumor virus from other known DNA polymerases.

Authors:  N C Goodman; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1971-09       Impact factor: 11.205

10.  The 3'-terminal nucleosides of the high molecular weight RNA of avian myeloblastosis virus.

Authors:  M L Stephenson; L S Wirthlin; J F Scott; P C Zamecnik
Journal:  Proc Natl Acad Sci U S A       Date:  1972-05       Impact factor: 11.205
View more
  2 in total

1.  Affinity chromatography of viral DNA polymerases on pyran-sepharose.

Authors:  J G Chirikjian; L Rye; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

2.  New observations concerning the chloroacetaldehyde reaction with some tRNA constituents. Stable intermediates, kinetics and selectivity of the reaction.

Authors:  J Biernat; J Ciesiołka; P Górnicki; R W Adamiak; W J Kryzosiak; M Wiewiórowski
Journal:  Nucleic Acids Res       Date:  1978-03       Impact factor: 16.971
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.