Literature DB >> 4366754

Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic conditions.

S Pontremoli, E Melloni, A De Flora, B L Horecker.   

Abstract

Fructose 1,6-bisphosphatase (EC 3.1.3.11) requires a free divalent metal and a metal chelate for optimum activity in the neutral pH range. The latter requirement can be satisfied by histidine, which appears to function as the chelating metabolite in vivo. Under fasting conditions, the concentrations of histidine in rabbit liver vary in the range required for activation of fructose bisphosphatase, and the enzyme itself is modified so that it becomes more responsive to histidine.

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Year:  1974        PMID: 4366754      PMCID: PMC388411          DOI: 10.1073/pnas.71.6.2166

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  14 in total

1.  The role of tryptophan in neutral fructose diphosphatase.

Authors:  S J Benkovic; W A Frey; C B Libby; J J Villafranca
Journal:  Biochem Biophys Res Commun       Date:  1974-03-15       Impact factor: 3.575

2.  Role of oleate in the regulation of "neutral" rabbit liver fructose 1,6-diphosphatase activity.

Authors:  C W Carlson; R C Baxter; E H Ulm; B M Pogell
Journal:  J Biol Chem       Date:  1973-08-25       Impact factor: 5.157

3.  Conversion of neutral to alkaline liver fructose 1,6-bisphosphatase: changes in molecular properties of the enzyme.

Authors:  S Pontremoli; E Melloni; A De Flora; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

4.  Activation of muscle fructose 1,6-diphosphatase by creatine phosphate and citrate.

Authors:  J Y Fu; R G Kemp
Journal:  J Biol Chem       Date:  1973-02-10       Impact factor: 5.157

5.  Rabbit liver fructose 1,6-diphosphatase. Properties of the native enzyme and their modification by subtilisin.

Authors:  S Traniello; E Melloni; S Pontremoli; C L Sia; R L Horecker
Journal:  Arch Biochem Biophys       Date:  1972-03       Impact factor: 4.013

6.  Activation of rabbit muscle fructose diphosphatase by EDTA and the effect of divalent cations.

Authors:  A Van Tol; W J Black; B L Horecker
Journal:  Arch Biochem Biophys       Date:  1972-08       Impact factor: 4.013

7.  Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting.

Authors:  S Pontremoli; E Melloni; F Salamino; A T Franzi; A De Flora; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

8.  The effects of starvation and alloxan-diabetes on the contents of citrate and other metabolic intermediates in rat liver.

Authors:  C Start; E A Newsholme
Journal:  Biochem J       Date:  1968-04       Impact factor: 3.857

9.  Changes in activity and molecular properties of fructose 1, 6-bisphosphatase during fasting and refeeding.

Authors:  S Pontremoli; E Melloni; F Salamino; A De Flora; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

10.  Activation of rabbit kidney fructose diphosphatase by Mg-EDTA, Mn-EDTA and Co-EDTA complexes.

Authors:  J S Rosenberg; Y Tashima; B L Horecker; S Pontremoli
Journal:  Arch Biochem Biophys       Date:  1973-01       Impact factor: 4.013

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  4 in total

1.  Hormonal effects on structure and catalytic properties of fructose 1,6-bisphosphatase.

Authors:  S Pontremoli; A De Flora; F Salamino; E Melloni; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

2.  Inhibition of liver fructose 1,6-bisphosphatase activity by Zn2+: reversal by imidazole pyruvate.

Authors:  P F Han; G Y Han; T W Cole; G S Owen; J Johnson
Journal:  Experientia       Date:  1978-06-15

3.  Dual role of Zn2+ as inhibitor and activator of fructose 1,6-bisphosphatase of rat liver.

Authors:  G A Tejwani; F O Pedrosa; S Pontremoli; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1976-08       Impact factor: 11.205

4.  Binding of Zn2+ to rat liver fructose-1,6-bisphosphatase and its effect on the catalytic properties.

Authors:  F O Pedrosa; S Pontremoli; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

  4 in total

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