| Literature DB >> 4357886 |
S Pontremoli, E Melloni, F Salamino, A T Franzi, A De Flora, B L Horecker.
Abstract
Exposure of rabbits to cold or fasting results in marked increases in the number and size of liver lysosomes, associated with increases in the total and "free" proteolytic activity. Changes in lysosomal morphology also indicate increased activity and fragility. These effects of cold and fasting are correlated with decreases in the levels of liver fructose bisphosphatase (EC 3.1.3.11) activity and changes in the molecular properties of the purified enzyme, including the loss of a small peptide containing the only tryptophan residue in the peptide chain.Entities:
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Year: 1973 PMID: 4357886 PMCID: PMC427304 DOI: 10.1073/pnas.70.12.3674
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205