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Literature DB >> 4363410

Concordant segregation of the expression of SV40 T antigen and human chromosome 7 in mouse-human hybrid subclones.

Abstract

Subcloning of Simian virus 40 (SV40) T antigen-positive mouse-human hybrids, derived from the fusion of mouse cells deficient in thymidine kinase with SV40-transformed Lesch Nyhan fibroblasts, resulted in their segregation into T antigen-positive and negative subclones. Positive correlation between the presence of human chromosome 7 and the expression of SV40 T antigen was established in the subclones examined. These results negate the possibility of a transfer of the SV40 genome to a mouse chromosome.

Entities: CellLine Disease Species

Mesh：

Substances：
Antigens, Viral

Year: 1974 PMID： 4363410 PMCID： PMC2139669 DOI： 10.1084/jem.139.5.1350

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

5 in total

1. Preferential retention of the human chromosome C-7 in human-(thymidine kinase deficient) mouse hybrid cells.

Authors: C M Croce; B B Knowles; H Koprowski
Journal: Exp Cell Res Date: 1973-12 Impact factor: 3.905

2. Genetic analysis with human--mouse somatic cell hybrids.

Authors: M Nabholz; V Miggiano; W Bodmer
Journal: Nature Date: 1969-07-26 Impact factor: 49.962

3. Detection of adenovirus type 12 neoantigen (s) in a continuous human amnion cell line (FL) by immunofluorescence.

Authors: J L Riggs; N Takemori; E H Lennette
Journal: Proc Soc Exp Biol Med Date: 1965-12

4. Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7.

Authors: C M Croce; A J Girardi; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1973-12 Impact factor: 11.205

5. Human regulatory gene for inducible tyrosine aminotransferase in rat-human hybrids.

Authors: C M Croce; G Litwack; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1973-04 Impact factor: 11.205

5 in total

17 in total

1. Another chromosomal assignment for a simian virus 40 integration site in human cells.

Authors: R Kucherlapati; S P Hwang; N Shimizu; J K McDougall; M R Botchan
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

2. Somatic cell hybrids between mouse peritoneal macrophages and simian-virus-40-transformed human cells: II. Presence of human chromosome 7 carrying simin virus 40 genome in cells of tumors induced by hybrid cells.

Authors: C M Croce; D Aden; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1975-04 Impact factor: 11.205

3. Assignment of gene(s) for cell transformation to human chromosome 7 carrying the simian virus 40 genome.

Authors: C M Croce; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1975-05 Impact factor: 11.205

4. Isolation of a new DNA marker in linkage disequilibrium with cystic fibrosis, situated between J3.11 (D7S8) and IRP.

Authors: X Estivill; C McLean; V Nunes; T Casals; P Gallano; P Scambler; R Williamson
Journal: Am J Hum Genet Date: 1989-05 Impact factor: 11.025

Review 5. Genetics of B-cell neoplasia.

Authors: C M Croce
Journal: Eur J Epidemiol Date: 1985-03 Impact factor: 8.082

9. Chromosome assignment of the T-antigen gene of simian virus 40 in African green monkey cells transformed by adeno 7-SV40 hybrid.

Authors: C M Croce; K Huebner; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1974-10 Impact factor: 11.205

Review 10. Human cell transformation by simian virus 40--a review.

Authors: G H Sack
Journal: In Vitro Date: 1981-01