Literature DB >> 4311792

Simian virus 40-induced T and tumor antigens.

C W Potter, B C McLaughlin, J S Oxford.   

Abstract

Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found.

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Year:  1969        PMID: 4311792      PMCID: PMC375911     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  18 in total

1.  Quantitative micro-complement fixation and its use in the study of antigenic structure by specific antigen-antibody inhibition.

Authors:  E WASSERMAN; L LEVINE
Journal:  J Immunol       Date:  1961-09       Impact factor: 5.422

2.  A method for determining the sedimentation behavior of enzymes: application to protein mixtures.

Authors:  R G MARTIN; B N AMES
Journal:  J Biol Chem       Date:  1961-05       Impact factor: 5.157

3.  Specific tumour antigen induced by chick embryo lethal orphan (CELO) virus.

Authors:  C W Potter; J S Oxford
Journal:  J Gen Virol       Date:  1969-03       Impact factor: 3.891

Review 4.  The oncogenic DNA viruses: a review of in vitro transformation studies.

Authors:  P H Black
Journal:  Annu Rev Microbiol       Date:  1968       Impact factor: 15.500

5.  Enzyme induction in SV40-infected green monkey kidney cultures.

Authors:  S Kit; D R Dubbs; P M Frearson; J L Melnick
Journal:  Virology       Date:  1966-05       Impact factor: 3.616

6.  Effects of tumour viruses on growth regulation in cultured cells.

Authors:  M G Stoker
Journal:  Lancet       Date:  1969-02-15       Impact factor: 79.321

Review 7.  Tumor-specific transplantation antigens: G. H. A. Clowes memorial lecture.

Authors:  G Klein
Journal:  Cancer Res       Date:  1968-04       Impact factor: 12.701

8.  A simple purification procedure for adenovirus type 12T and tumor antigens and some of their properties.

Authors:  G Tockstein; H Polasa; M Piña; M Green
Journal:  Virology       Date:  1968-11       Impact factor: 3.616

9.  Production of high-titer antibody in serum and ascitic fluid of hamsters for a variety of virus-induced tumor antigens.

Authors:  R V Gilden; T G Beddow; R J Huebner
Journal:  Appl Microbiol       Date:  1967-05

10.  Nonidentiy of some simian virus 40-induced enzymes with tumor antigen.

Authors:  S Kit; J L Melnick; M Anken; D R Dubbs; R A De Torres; T Kitahara
Journal:  J Virol       Date:  1967-08       Impact factor: 5.103

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  16 in total

1.  Measurements of the molecular size of the simian virus 40 large T antigen.

Authors:  J D Griffin; S Light; D M Livingston
Journal:  J Virol       Date:  1978-07       Impact factor: 5.103

2.  Characterization of T antigen in cells infected with a temperature-sensitive mutant of simian virus 40.

Authors:  T Kuchino; N Yamaguchi
Journal:  J Virol       Date:  1975-06       Impact factor: 5.103

3.  Regulation of tumor antigen synthesis by simain virus 40 gene A.

Authors:  P Tegtmeyer; M Schwartz; J K Collins; K Rundell
Journal:  J Virol       Date:  1975-07       Impact factor: 5.103

4.  Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen.

Authors:  D T Simmons; W Chou; K Rodgers
Journal:  J Virol       Date:  1986-12       Impact factor: 5.103

5.  Isolation of the SV40 induced tumor ("T") antigen from transformed hamster kidney cells.

Authors:  G Spira; M Popescu; S Cymbalista; N Biezunski; N Goldblum
Journal:  Arch Gesamte Virusforsch       Date:  1972

6.  Detection and characterization of multiple forms of simian virus 40 large T antigen.

Authors:  E Fanning; B Nowak; C Burger
Journal:  J Virol       Date:  1981-01       Impact factor: 5.103

7.  Association of simian virus 40 T antigen with replicating nucleoprotein complexes of simian virus 40.

Authors:  M Segawa; S Sugano; N Yamaguchi
Journal:  J Virol       Date:  1980-08       Impact factor: 5.103

8.  Phosphorylation and dephosphorylation alter the structure of D2 hybrid T antigen.

Authors:  E A Baumann; R Hand
Journal:  J Virol       Date:  1982-10       Impact factor: 5.103

9.  Different forms of simian virus 40 large tumor antigen varying in their affinities for DNA.

Authors:  D Gidoni; A Scheller; B Barnet; P Hantzopoulos; M Oren; C Prives
Journal:  J Virol       Date:  1982-05       Impact factor: 5.103

10.  Time-dependent maturation of the simian virus 40 large T antigen-p53 complex studied by using monoclonal antibodies.

Authors:  R B Carroll; E G Gurney
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

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