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Literature DB >> 429010

Isoelectric focusing of rare transferrin (Tf) variants and common TfC subtypes.

Abstract

TransferrinC (TfC) subtypes were determined by isoelectric focusing (PAGIF) on samples from 90 carriers of the TFB and TfD alleles. In all cases of CB and CD heterozygotes only one of the two common subtypes of the TfC allele, TfC1 or TfC2, was observed. This is considered strong support for the hypothesis of two common alleles at the Tf locus. The different isofocusing patterns of rare B and D variants are compared with the results obtained after agarose gel electrophoresis (AGE).

Entities: Chemical Gene

Mesh：

Substances：
Transferrin

Year: 1979 PMID： 429010 DOI： 10.1007/bf00278905

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

4 in total

1. [Transferrin variants: significance and identification in paternity cases (author's transl)].

Authors: G Mauff; E Doppelfeld; W Weber
Journal: Z Immunitatsforsch Exp Klin Immunol Date: 1975-08

2. [Studies on C'3-polymorphism ( 1c -globulin). Gene frequencies and family studies in blood donors from Hessen and a Bantu population].

Authors: P Kühnl; W Spielmann
Journal: Humangenetik Date: 1972

3. An improved method for the identification of Gc1 subtypes (group-specific component) by isoelectric focusing.

Authors: P Kühnl; W Spielmann; M Loa
Journal: Vox Sang Date: 1978 Impact factor: 2.144

4. Transferrin: evidence for two common subtypes of the TfC allele.

Authors: P Kühnl; W Spielmann
Journal: Hum Genet Date: 1978-07-12 Impact factor: 4.132

4 in total

7 in total

1. A third common allele in the transferrin system, TfC3, detected by isoelectric focusing.

Authors: P Kühnl; W Spielmann
Journal: Hum Genet Date: 1979 Impact factor: 4.132

2. A new procedure for the determination of transferrin C (Tf C) subtypes by isoelectric focusing. Existence of two additional alleles, Tf C4 and Tf C5.

Authors: J Constans; P Kühnl; M Viau; W Spielmann
Journal: Hum Genet Date: 1980 Impact factor: 4.132

Isoelectric focusing of rare transferrin (Tf) variants and common TfC subtypes.

1. [Transferrin variants: significance and identification in paternity cases (author's transl)].

2. [Studies on C'3-polymorphism ( 1c -globulin). Gene frequencies and family studies in blood donors from Hessen and a Bantu population].

3. An improved method for the identification of Gc1 subtypes (group-specific component) by isoelectric focusing.

4. Transferrin: evidence for two common subtypes of the TfC allele.

1. A third common allele in the transferrin system, TfC3, detected by isoelectric focusing.

2. A new procedure for the determination of transferrin C (Tf C) subtypes by isoelectric focusing. Existence of two additional alleles, Tf C4 and Tf C5.

3. Human transferrin (Tf) and group-specific component (Gc) subtypes in Tunisia.

4. Transferrin D protein variants in the diagnosis of congenital disorders of glycosylation (CDG).

5. Isoelectric focusing with immobilized pH gradients for the analysis of transferrin (Tf) subtypes and variants.

6. Gene frequencies of transferrin (TfC) subtypes in Western Germany (Düsseldorf region).

7. Genetic variants of transferrin in cystic fibrosis.