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Literature DB >> 10819023

Human transferrin (Tf) and group-specific component (Gc) subtypes in Tunisia.

M P Lefranc¹, J Chibani, A N Helal, K Boukef, J Seger, G Lefranc.

Abstract

Simultaneous subtyping of two genetic markers--group-specific component (Gc) and transferrin (Tf)--by electrofocusing enabled us to compute the following gene frequencies for the Tunisian population: Gc1S, 0.525; Gc1F, 0.260; Gc2, 0.215; TfC1, 0.770; TfC2, 0.215; TfD1, 0.015. The frequencies of TfD, TfC2, and Gc1 are higher than those found in Caucasoid populations and can be explained by Negroid contribution. A selective advantage related to the metabolic role of this vitamin D-binding protein does not seem very likely for any particular Gc type or subtype. It is postulated that the differences in the frequencies of the Gc alleles might be related to selective advantage for genes belonging to other genetic systems originally closely linked to either Gc1 or to Gc2 alleles.

Entities: Gene Species

Mesh：

Substances：

Year: 1981 PMID： 10819023 DOI： 10.1007/bf00278855

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

22 in total

1. Genetic studies in Saudi Arabia: red cell enzyme, haemoglobin and serum protein polymorphisms.

Authors: H W Goedde; H G Benkmann; D P Agarwal; L Hirth; U Bienzle; M Dietrich; H H Hoppe; J Orlowski; E Kohne; E Kleihauer
Journal: Am J Phys Anthropol Date: 1979-02 Impact factor: 2.868

2. Gm, Am and Km immunoglobulin allotypes of two populations in Tunisia.

Authors: G Lefranc; G de Lange; L Rivat; A Langaney; M P Lefranc; F Ellouze; G Sfar; M Sfar; E van Loghem
Journal: Hum Genet Date: 1979 Impact factor: 4.132

3. Gc subtypes demonstrated by isoelectric focusing: further data and description of new variants among an African sample (Fula) from Senegal.

Authors: J Constans; M Viau; G Pison; A Langaney
Journal: Jinrui Idengaku Zasshi Date: 1978-06

4. The distribution of the group-specific component (Gc) subtypes in Japanese.

Authors: K Omoto; K Miyake
Journal: Jinrui Idengaku Zasshi Date: 1978-06

5. Common and uncommon immunoglobulin haplotypes among Lebanese communities.

Authors: G Lefranc; L Rivat; J L Serre; J M Lalouel; G Pison; J Loiselet; C Ropartz; G de Lange; E van Loghem
Journal: Hum Genet Date: 1978-03-17 Impact factor: 4.132

6. Group-specific component: evidence for two subtypes of the Gc1 gene.

Authors: J Constans; M Viau
Journal: Science Date: 1977-12-09 Impact factor: 47.728

7. Analysis of the Gc polymorphism in human populations by isoelectrofocusing on polyacrylamide gels. Demonstration of subtypes of the Gc allele and of additional Gc variants.

Authors: J Constans; M Viau; H Cleve; G Jaeger; J C Quilici; M J Palisson
Journal: Hum Genet Date: 1978-02-23 Impact factor: 4.132

8. Polymorphism of the third component (C3) of complement and of Transferrin (Tf) in Belgium.

Authors: B Hoste; J Brocteur; J Suys; A Andre
Journal: Z Rechtsmed Date: 1977-07-05

9. Transferrin: evidence for two common subtypes of the TfC allele.

Authors: P Kühnl; W Spielmann
Journal: Hum Genet Date: 1978-07-12 Impact factor: 4.132

10. Isoelectric focusing of rare transferrin (Tf) variants and common TfC subtypes.

Authors: P Kühnl; W Spielmann; W Weber
Journal: Hum Genet Date: 1979-01-19 Impact factor: 4.132

5 in total

1. Frequency of human A gamma 75Thr globin chain in a population from Tunisia.

Authors: M P Lefranc; G Lefranc; M Farhat; R Jmour; K Boukef; Y Beuzard; F Galacteros; J Rosa
Journal: Hum Genet Date: 1981 Impact factor: 4.132

Review 2. Ethnic variation in vitamin D-binding protein (GC): a review of isoelectric focusing studies in human populations.

Authors: M I Kamboh; R E Ferrell
Journal: Hum Genet Date: 1986-04 Impact factor: 4.132